Gaois

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  1. SOCIAL QUESTIONS|health|medical science|toxicology

    #648583

    IATE #3542143
    tástáil micreanúicléis in vitro i gcealla mamach Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    in vitro mammalian cell micronucleus test | MNvit assay | in vitro mouse micronucleus test
    en
    Definition "genotoxicity test for the detection of micronuclei [ IATE:1033008 ] (MN) in the cytoplasm [ IATE:1077370 ] of interphase [ IATE:1530134 ] cells" Reference "OECD. Environment Directorate. Chemical Safety and Biosafety. Testing of Chemicals. In Vitro Mammalian Cell Micronucleus Test (MNvit) http://www.oecd.org/LongAbstract/0,3425,en_2649_34377_39780113_1_1_1_1,00.html [13.4.2012]"
    Comment "Micronuclei [ IATE:1033008 ] may originate from acentric chromosome [ IATE:1507541 ] fragments (i.e. lacking a centromere [ IATE:1620877 ]), or whole chromosomes that are unable to migrate to the poles during the anaphase [ IATE:1502711 ] stage of cell division [ IATE:1544625 ]. The assay detects the activity of clastogenic [ IATE:1684795 ] and aneugenic chemicals [ IATE:1588368 ] (substances and mixtures) (1) (2) in cells that have undergone cell division during or after exposure to the test substance."