Gaois

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2 results

  1. SCIENCE|natural and applied sciences|life sciences|biology

    #634475

    IATE #1685032
    topaisiméaráis Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    topaisiméaráis DNA Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    Topoisomerase
    de
    Definition Enzym, das die räumliche Struktur der DNS bestimmt und verändert Reference Roche-Lexikon Medizin,2.Auflage,1991,Urban&Schwarzenberg,München
    DNA topoisomerase | topoisomerase
    en
    Definition enzyme that participates in the overwinding or underwinding of DNA Reference "Wikipedia > Tomoisomerase (19.4.2021)"
    ADN topo-isomérase
    fr
    Definition enzyme capable de modifier le surenroulement de l'ADN en coupant l'un ou les deux brins de la molécule double-brin, réalisant l'interconversion des topo-isomères de l'ADN Reference Dict.de génétique,CILF,1991
  2. SOCIAL QUESTIONS|health|pharmaceutical industry · SCIENCE|natural and applied sciences|life sciences

    #617994

    IATE #1079226
    coscaire topaisiméaráise Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    Topoisomerasehemmer | Topoisomerase-Hemmer | Topoisomerase-Inhibitor
    de
    Definition Hemmstoff der Topoisomerase; Zytostatikum Reference "Roche Lexikon Medizin, Urban & Fischer: 2003, 5. Aufl., s. v. „C. thoracis“, www.roche.de&content=/lexikon/suche.html" rel="noopener noreferrer" target="_blank">https://www.roche.de/lexikon/index.htm?loc=www.roche.de&content=/lexikon/suche.html> (26.10.2017)"
    Comment Wirkstoff: a) Topoisomerase-I-Inhibitoren: Topotecan u. Irinotecan; b) Topoisomerase-II-Inhibitoren: Etoposid u. Teniposid (Podophyllotoxin-Derivate); Wirkung: verursachen Brüche der DNS-Stränge, dadurch Hemmung der Replikation. Nebenwirkungen: u.a. Myelosuppression, Nausea, Erbrechen, Alopezie u. v.a. unter Irinotecan schwere Durchfälle.
    topoisomerase inhibitor | inhibitors
    en
    Definition "group of agents designed to interfere with the action of topoisomerase enzymes (topoisomerase I and II), which are enzymes that control the changes in DNA structure by catalyzing the breaking and rejoining of the phosphodiester backbone of DNA strands during the normal cell cycle [ IATE:1544625 ]" Reference "Wikipedia http://en.wikipedia.org/wiki/Topoisomerase_inhibitor [21.9.2010]"
    Comment In recent years, topoisomerases have become popular targets for cancer chemotherapy treatments. They can also function as antibacterial agents.
    inhibiteur de la topoisomérase
    fr
    Definition il inhibe la capacité de la topoisomérase à relier les deux bouts coupés des brins de l'ADN, tue la cellule, car les brins libérés perturbent mortellement son fonctionnement Reference Pour la Science,Novembre 1996