INDUSTRY|chemistry · SCIENCE|natural and applied sciences|life sciences
- cioglocsaigionáis Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
- ga
- COX | cyclooxygenase
- en
- Definition enzyme that catalyses the transformation of arachidonic acid [ IATE:1076668 ] released from membrane phospholipids [ IATE:1450511 ] as a response to inflammatory stimuli, into prostaglandins [ IATE:1450544 ] and leukotrienes [ IATE:1463911 ], the former of which establish the inflammatory response Reference COM-EN, based on:Amrita Sarkar. Effect of NSAIDs on Cyclooxygenase-1. Middlebury College http://cat.middlebury.edu/~chem/chemistry/class/bio/ch314/presentations/amrita/ [18.5.2012]
- Comment At present, three COX isoenzymes [ IATE:1073670 ] are known: COX-1, which is constitutive, meaning that its concentration in the body remains stable, and is stimulated continuously by normal body physiology;COX-2, discovered in 1991, which is stimulated only as a part of an immune response and COX-3, discovered in 2002.
- cyclo-oxygénase | cyclooxygénase
- fr
- Comment An enzyme --