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4 thoradh

  1. SOCIAL QUESTIONS|health|medical science
    deisiú trí eisceadh núicléitídí Tagairt Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    nucleotide excision repair | NER
    en
    Sainmhíniú repair pathway, involved in the removal of a variety of bulky DNA lesions Tagairt Leon H.F. Mullenders, Anne Stary and Alain Sarasin. Nucleotide excision repair. Atlas of Genetics and Cytogenetics in Oncology and Haematology http://atlasgeneticsoncology.org/Deep/ExcisRepairID20014.html [10.2.2012]
    Nóta NER is a complex process in which basically the following steps can be distinguished:(i) recognition of a DNA lesion;(ii) separation of the double helix at the DNA lesion site;(iii) single strand incision at both sides of the lesion;(iv) excision of the lesion-containing single stranded DNA fragment;(v) DNA repair synthesis to replace the gap and(vi) ligation of the remaining single stranded nick.
    réparation par excision de nucléotides | REN
    fr
    Sainmhíniú système de réparation versatile qui permet d'éliminer une grande variété de dommages de l'ADN Tagairt COM-FR d'après Test fonctionnel de mesure des activités enzymatiques de réparation de l’ADN par excision resynthèse sur support miniaturisé: mise au point et applications, thèse présentée par Jean-François Millau (2006), Université Joseph-Fourier de Grenoble, http://tel.archives-ouvertes.fr/docs/00/12/68/58/PDF/These_Millau.pdf [12.2.2014]
    Nóta On peut décomposer ce mécanisme en cinq étapes: la reconnaissance du dommage, l’incision du brin d’ADN contenant le dommage, son excision, la re-synthèse du brin excisé, et enfin la ligation du brin néoformé. Voir: Test fonctionnel de mesure des activités enzymatiques de réparation de l’ADN par excision resynthèse sur support miniaturisé: mise au point et applications, thèse présentée par Jean-François Millau (2006), Université Joseph-Fourier de Grenoble, http://tel.archives-ouvertes.fr/docs/00/12/68/58/PDF/These_Millau.pdf [12.2.2014]
  2. SCIENCE|natural and applied sciences|life sciences
    deisiú DNA trí eisceadh Tagairt Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    deisiú trí eisceadh Tagairt Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    Reparatur der DNA durch Exzisionsresynthese
    de
    excision and repair | excision repair | excision repair process
    en
    Sainmhíniú the single strand repair mechanism of DNA wherein the damaged segment is removed and subsequently replaced through DNA synthesis using the undamaged strand as a template Tagairt COM-EN, based on:Hedgehog Signaling Glossary. Excision repair http://groups.molbiosci.northwestern.edu/holmgren/Glossary/Definitions/Def-E/excision_repair.html [1.3.2011]
    Nóta These mechanisms include:- Base excision repair [ IATE:2109769 ] - Nucleotide excision repair- Mismatch repair [ IATE:1686084 ]
    réparation de l'ADN par excision-resynthèse
    fr
    Sainmhíniú système de réparation fidèle de l'ADN qui agit sur la lésion d'un seul brin de l'ADN double brin Tagairt Dict.de génétique,CILF,1991
  3. SCIENCE|natural and applied sciences|life sciences · SOCIAL QUESTIONS|health|medical science
    deisiú fadphaiste Tagairt Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    deisiú fadphaiste trí eisceadh bunaidh Tagairt Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    long-patch base-excision repair | LP-BER | long-patch DNA repair | longpatch repair | long-patch BER | long-patch repair
    en
    Sainmhíniú base excision repair mechanism [ IATE:2109769 ] involving more than one nucleotide Tagairt COM-EN, based on: Ulrike Sattler, Philippe Frit, Bernard Salles, and Patrick Calsou. Long-patch DNA repair synthesis during base excision repair in mammalian cells. EMBO Rep. 2003 April; 4(4): 363–367 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1319152/ [1.3.2011]
    Nóta See also short patch repair IATE:1584279
    réparation de longues séquences
    fr
  4. SCIENCE|natural and applied sciences|life sciences
    deisiú trí eisceadh bunaidh Tagairt Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    base excision repair | BER
    en
    Sainmhíniú one of the three excision repair mechanisms that employ all organisms in order to repair their DNA by removing small, non-helix-distorting base lesions from the genome Tagairt COM-EN, based on:Wikipedia http://en.wikipedia.org/wiki/Base_excision_repair [1.3.2011]
    Nóta The related nucleotide excision repair pathway repairs bulky helix-distorting lesions. BER is important for removing damaged bases that could otherwise cause mutations by mispairing or lead to breaks in DNA during replication.