Gaois

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7 results

  1. SCIENCE|natural and applied sciences|life sciences · SCIENCE|natural and applied sciences|life sciences|biology
    teachtaire RNA Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
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    mRNA Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
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    teachtaire RNA aibí Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
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    mRNA aibí Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
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    m-RNS | definitive Messenger-RNA | m-RNA | Matrizen-RNA | Messenger-RNA | Boten-RNA
    de
    mature messenger RNA | messenger RNA | mRNA | mature mRNA
    en
    Definition single-stranded RNA which contains only exons and is complementary to one of the DNA strands of a protein-coding gene Reference COM-Terminology Coordination, based on:1) Biology Online. 'Mature mRNA' (25.5.2020)2) Michael Greenwood. 'What are Introns and Exons?' (25.5.2020) News-Medical Life Sciences.3) Clancy, S. (2008) 'RNA splicing: introns, exons and spliceosome' (25.5.2020). Nature Education 1(1):314) Lawrence C. Brody. Messenger RNA (mRNA) (25.5.2020). National Human Genome Research Institute
    Comment For most eukaryotic genes (and some prokaryotic ones), the initial RNA that is transcribed from a gene's DNA template must be processed before it becomes a mature messenger RNA (mRNA) that can direct the synthesis of protein.
    ARN messager définitif | ARN messager mature | ARNm | ARN messager
    fr
    Definition 1) L'ARN messager ne contient que quatre bases: A, G, C, U. Il est synthétisé dans le noyau au moment de la transcription, au cours de laquelle la séquence en bases d'un des brins d'ADN est transcrite en un brin unique d'ARNm. Les bases de celui-ci sont complémentaires de celles du brin d'ADN transcrit. L'ARN messager passe ensuite dans les ribosomes où il contrôle la mise en place des aminoacides au cours de la synthèse des protéines 2) ARN messager obtenu après excision-ligature de l'ARN prémessager:sa séquence est intégralement traductible en une protéine Reference Lehninger,p.316
  2. SCIENCE|natural and applied sciences|life sciences|biology
    mRNA monaiciostrónach Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
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    monozystronischer mRNA
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    monocistronic mRNA
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    Definition mRNA that encodes only one protein Reference Phil McClean. PLSC 731 - Plant Molecular Genetics (17.8.2020) > Transcription > 'Transcription Products' (17.8.2020)
    Comment All eukaryotic mRNAs are monocistronic
    ARN messager monocistronique | ARN monocistronique
    fr
    Definition molécule d'ARN messager produite par transcription d'un gène de structure(cistron)unique:elle est particulièrement présente chez les Eucaryotes ; ARN ne comportant qu'une seule information génétique Reference Dict.de génétique,CILF,1991 ; arrêté du 14/09/90 relatif à la terminologie du génie génétique,JORF 26/09/90
  3. SCIENCE|natural and applied sciences|life sciences|biology
    mRNA polaiciostrónach Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
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    polycistronic mRNA
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    Definition mRNA that encodes several proteins and is characteristic of many bacterial and chloroplast mRNAs Reference Phil McClean. PLSC 731 - Plant Molecular Genetics (17.8.2020) > Transcription > 'Transcription Products' (17.8.2020)
    ARNm polycistronique
    fr
    Definition ARN messager contenant plusieurs cistrons, et donc codant pour plusieurs chaînes polypeptidiques distinctes Reference arrêté du 14/09/90 relatif à la terminologie du génie génétique,JORF 26/09/90
  4. SCIENCE|natural and applied sciences|life sciences|biology
    próiseáil mRNA Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
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    aibiú mRNA Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
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    Reifung der mRNS
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    mRNA maturation | RNA maturation | mRNA processing | RNA processing
    en
    Definition 5' capping, splicing, 3'-end processing of pre-mRNA, that take place in the cell nucleus before mRNAcan be exported from the nucleus to the cytoplasm in order to be translated Reference COM-Terminology Coordination, based on: Hocine S, Singer RH, Grünwald D. 'RNA processing and export' (17.11.2020). Cold Spring Harb Perspect Biol. 2010;2(12):a000752. doi:10.1101/cshperspect.a000752
    maturation de l'ARN messager
    fr
    Definition On sait maintenant que l'ADN est transcrit d'abord en ARN pré-messager. Pour quitter le noyau, l'ARN doit être liberé de ses introns par excision-soudure. Ce processus est appelé maturation Reference Génétique,p.93
  5. SCIENCE|natural and applied sciences|life sciences|biology
    spladhsáil mhalartach mRNA Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
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    spladhsáil mhalartach Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
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    differentielles Splicing
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    alternative pre-mRNA splicing | alternative mRNA splicing | alternative splicing
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    Definition mechanism through which particular exons of a gene may be included within or excluded from the final, processed messenger RNA (mRNA) produced from that gene by selecting different combinations of splice sites within a pre-mRNA Reference COM-Terminology Coordination, based on: - Wikipedia > Alternative splicing (27.4.2021)- D.S. Greenberg, H.Soreq., 'Alternative Splicing' (18.11.2020), In: Reference Module in Biomedical Sciences Brenner's Encyclopedia of Genetics (Second Edition) 2013, Pages 97-98
    Comment It differs from constitutive splicing in that alternative exons might or might not be included, and there may be exon skipping, intron retention, alternative 5′ and 3′ splice sites and mutually exclusive exons, leading to the generation of potentially hundreds of proteins from a single mRNA. In some instances, multiple mRNAs are generated that all lead to the translation of the same protein product, for example brain-derived neurotrophic factor (BDNF).
    épissage alternatif de l'ARNm | épissage alternatif de l'ARN messager | épissage différentiel
    fr
    Definition existence de plusieurs schémas d'épissage d'un transcrit primaire aboutissant à la formation de différents RNA messagers, et pouvant donner lieu à la synthèse de plusieurs protéines différentes Reference Schorderet,D.,Gloss.génétique,Division de génétique médicale,CHUV,Lausanne,1993
  6. SOCIAL QUESTIONS|health|pharmaceutical industry
    teicneolaíocht mRNA Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    Context 'Baineann na vacsaíní COVID-19 a d’fhorbair BioNTech/Pfizer agus Moderna agus atá údaraithe lena n-úsáid san Aontas, chomh maith leis an vacsaín a d’fhorbair CureVac a bhfuil athbhreithniú rollach á dhéanamh ag EMA air faoi láthair, úsáid as teicneolaíocht mRNA.' Reference 'An Chomhairle Eorpach,' https://www.consilium.europa.eu/ga/policies/coronavirus/covid-19-research-and-vaccines/ [30.3.2021]
    mRNA technology
    en
    Definition technology for the development of theurapetics and vaccines based on the properties of mRNA Reference COM-Terminology Coordination, based on:- Schlake T, Thess A, Fotin-Mleczek M, Kallen KJ. 'Developing mRNA-vaccine technologies' (26.6.2020). RNA Biol. 2012 Nov;9(11):1319-30. Epub 2012 Oct 12. PMID: 23064118; PMCID: PMC3597572.- Ingmar Hoerr. 'mRNA Will Revolutionise the Biopharmaceutical Industry' (26.6.2020). DDW
  7. SOCIAL QUESTIONS|health|pharmaceutical industry|pharmaceutical product|vaccine
    vacsaín mRNA Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    Context 'Tar éis duit vacsaín mRNA a fháil, cruthaíonn do cholainn antasubstaintí a chabhraíonn leat ionfhabhtú a throid má théann víreas isteach i do cholainn sa todhchaí.' Reference 'Feidhmeannacht na Seirbhíse Sláinte,' https://www2.hse.ie/gaeilge/coroinvireas/vacsan-covid-19-mrna-agus-veicteoir-vreasach.html [6.4.2021]
    mRNA vaccine | mRNA-based vaccine
    en
    Definition vaccine that works by introducing an mRNA sequence (the molecule which tells cells what to build) which is coded for a disease specific antigen which elicits an immune response once expressed in the infected human cells Reference COM-Terminology Coordination, based on:University of Cambridge. PHG Foundation. RNA vaccines: an introduction (31.7.2020)
    vaccin à ARN | vaccin à ARNm | vaccin à ARN messager
    fr