SOCIAL QUESTIONS|health|pharmaceutical industry
- ceangal plasmaphróitéine Tagairt Faomhadh an téarma seo mar chuid de Thionscadal Lex
- ga
- Comhthéacs 'Déanfar cur síos ar dháileadh an táirge íocshláinte tréidliachta sa spriocainmhí. Breithneofar an fhéidearthacht go dtarlódh ceangal plasmaphróitéine nó gluaiseacht isteach i mbainne nó in uibheacha agus carnadh comhdhúile lipifileacha.' Tagairt "Rialachán (AE) 2019/6 maidir le táirgí íocshláinte tréidliachta agus lena n-aisghairtear Treoir 2001/82/CE, CELEX:32019R0006/GA"
- ceangal próitéine Tagairt Faomhadh an téarma seo mar chuid de Thionscadal Lex
- ga
- Comhthéacs 'Déanfar cur síos ar dháileadh an táirge íocshláinte tréidliachta sa spriocainmhí. Breithneofar an fhéidearthacht go dtarlódh ceangal plasmaphróitéine nó gluaiseacht isteach i mbainne nó in uibheacha agus carnadh comhdhúile lipifileacha.' Tagairt "Rialachán (AE) 2019/6 maidir le táirgí íocshláinte tréidliachta agus lena n-aisghairtear Treoir 2001/82/CE, CELEX:32019R0006/GA"
- plasma protein binding | protein binding
- en
- Sainmhíniú interaction in which a drug binds to the proteins within blood plasma Tagairt "COM-Terminology Coordination, based on:Wikipedia. Plasma protein binding, http://en.wikipedia.org/wiki/Plasma_protein_binding [8.1.2014]"
- Nóta A drug in blood exists in two forms: bound and unbound. Depending on a specific drug's affinity for plasma protein, a proportion of the drug may become bound to plasma proteins, with the remainder being unbound. If the protein binding is reversible, then a chemical equilibrium will exist between the bound and unbound states, such that: Protein + drug ⇌ Protein-drug complexit is the unbound fraction which exhibits pharmacologic effects. It is also the fraction that may be metabolized and/or excreted.The bound portion may act as a reservoir or depot from which the drug is slowly released as the unbound form. Since the unbound form is being metabolized and/or excreted from the body, the bound fraction will be released in order to maintain equilibrium.