Gaois

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  1. INDUSTRY|chemistry|chemical compound · SCIENCE|natural and applied sciences|life sciences

    #558675

    IATE #1479696
    núicléisíd Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    Nukleosid | Nucleosid
    de
    Definition Nukleotid-und somit Nukleinsaeurebaustein aus Pentose und Base, d.h.Mononukleotid ohne Phosphorsaeuretest Reference Reallexikon der Medizin,1966,Urban und Schwarzenberg,München
    nucleoside
    en
    Definition purine or pyrimidine base [ IATE:1460683 ] attached to ribose [ IATE:1479345 ] or deoxyribose [ IATE:1479358 ] Reference ‘nucleoside’ (27.4.2020), Robert C. King, William D. Stansfield and Pamela K. Mulligan, A Dictionary of Genetics (7 ed.), Oxford University Press, 2007.
    Comment The nucleosides commonly found in DNA or RNA are cytidine, cytosine deoxyriboside, thymidine, uridine, adenosine, adenine deoxyriboside, guanosine, and guanine deoxyriboside. Note that thymidine is a deoxyriboside and cytidine, uridine, adenosine, and guanosine are ribosides
    nucléoside
    fr
    Definition nom générique des osides formés par l'union d'un pentose(ribose ou désoxyribose)et d'une base purique ou pyrimidique et comprenant les ribosides(à base de ribose)et les désoxyribosides(à base de désoxyribose) Reference Duval,Clément,Duval,Raymonde,Dictionnaire de la Chimie et de ses Applications,1978,Technique et Documentation,Paris
    Nuc | Y | Pyd | Puo | N | R
    mul
  2. SOCIAL QUESTIONS|health|pharmaceutical industry

    #565170

    IATE #1687059
    analóg núicléisíde Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    Nukleosidanalog | Nukleosid-Analogon | Nukleosidanalogon
    de
    Definition Substanzen, die natürlichen Nukleosiden ähneln, wie z. B. die nukleosidischen Reverse-Transkriptase-Inhibitoren (NRTI), und als Arzneistoffe vor allem in der antiviralen Therapie angewendet werden, z.B. gegen HIV, HBV und HBC Reference DocCheckFlexikon, s. v. „Nukleosidanalogon“, http://flexikon.doccheck.com/de/Nukleosidanalogon (24.10.2017)
    nucleoside analogue | nucleoside analog
    en
    Definition synthetic molecule that resembles a naturally occuring nucleoside, but that lacks a bond site needed to link it to an adjacent nucleotide Reference 'nucleoside analog' (19.10.2021). Hedgehog Signaling Glossary
    Comment Nucleoside analogues (NA) constitute an important class of antimetabolites used in the treatment of hematological malignancies and, more recently, in solid tumors. These therapeutic compounds mimic physiological nucleosides in terms of uptake and metabolism and are incorporated into newly synthesized DNA resulting in synthesis inhibition and chain termination. Some of these drugs also inhibit key enzymes involved in the generation of the purine and pyrimidine nucleotides and RNA synthesis, and directly activate the caspase cascade. All of these effects may lead to cell death.
    analogue nucléosidique | analogue de nucléoside
    fr
    Definition composé synthétique similaire à l'un des nucléotides présents dans l'ADN ou l'ARN d'un virus ou d'un rétrovirus Reference Act Up-Paris,Gloss.sida,janvier 1998