Gaois

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  1. SOCIAL QUESTIONS|health|medical science

    #544172

    IATE #1073382
    láthair COS Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    cos-Stelle
    de
    cos site
    en
    Definition 12-nucleotide1 segment of single-stranded DNA2 that exists at both ends of the bacteriophage1 lambda's double-stranded genome1 nucleotide [ IATE:1073318 ]2 single-stranded DNA [ IATE:1073344 ]3 bacteriophage [ IATE:1449959 ] Reference OECD. Test No. 488: Transgenic Rodent Somatic and Germ Cell Gene Mutation Assays. OECD Guidelines for the Testing of Chemicals, Section 4. ISSN: 2074-5788 (online). ISBN: 9789264203907 (PDF), http://www.oecd-ilibrary.org/docserver/download/9713251e.pdf?expires=1413541585&id=id&accname=guest&checksum=D70FC5C978E208B6186F77E45D428931 [17.10.2014]
    Comment Cos sites are all that is necessary for packaging DNA into phage particles. The lambda DNA forms long concatamers, each lambda genome being joined to the next one through the cos site. The packaging enzymes chop the concatamer up into lambda-sized pieces by recognizing two cos sites 35-45kb apart and cleaving this unit which is then packaged into a phage.
    site COS
    fr
    Definition site correspondant aux extrémités cohésives du génome du phage lambda Reference arrêté du 14/09/90 relatif à la terminologie du génie génétique,JORF 26/09/90