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    Folaíonn na breathnuithe seo ainmhithe le loit choirneacha de ghrád 4 agus frithghníomhuithe troma eile (e.g., scrios na coirne) a bhreathnaítear am ar bith i rith na tástála, chomh maith le teimhneacht choirneach mharthanach, mílí na coirne ag substaint ruaime, greamaitheacht, pannus agus cur isteach ar fheidhmiú an inteacháin nó éifeachtaí eile a lagaíonn an t-amharc.

    These observations include animals with grade 4 cornea lesions and other severe reactions (e.g., destruction of cornea) observed at any time during the test, as well as persistent corneal opacity, discoloration of the cornea by a dye substance, adhesion, pannus, and interference with the function of the iris or other effects that impair sight.

    Regulation (EC) No 1272/2008 of the European Parliament and of the Council of 16 December 2008 on classification, labelling and packaging of substances and mixtures, amending and repealing Directives 67/548/EEC and 1999/45/EC, and amending Regulation (EC) No 1907/2006