SOCIAL QUESTIONS|health|pharmaceutical industry · SCIENCE|natural and applied sciences|life sciences
- béite-lachtamáisí le speictream leathnaithe Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
- ga
- ESBL | ESBLs | extended-spectrum beta-lactamase | lactamases | extended-spectrum β-lactamase
- en
- Definition "any of the enzymes that may be produced by Gram negative bacteria and confer them resistance to expanded-spectrum cephalosporins [ IATE:1361346 ] by hydrolysing extended-spectrum cephalosporins with an oxyimino side chain" Reference "COM-EN, based on:- Wikipedia > Beta-lactamase http://en.wikipedia.org/wiki/Beta-lactamase#Extended-spectrum_beta-lactamase_.28ESBL.29 [6.6.2011 ] - Paterson D. L., Bonomo R.A., ""Extended-Spectrum β-Lactamases: a Clinical Update"" in Clinical Microbiology Reviews October 2005 vol. 18 no. 4 657-686 http://cmr.asm.org/content/18/4/657.full [18.10.2013]"
- Comment "The commonly expressed plasmid-encoded β-lactamases confer resistance to penicillins but not to expanded-spectrum cephalosporins. There is no consensus of the precise definition of ESBLs. A commonly used working definition is that the ESBLs are β-lactamases capable of conferring bacterial resistance to the penicillins, first-, second-, and third-generation cephalosporins, and aztreonam (but not the cephamycins or carbapenems) by hydrolysis of these antibiotics, and which are inhibited by β-lactamase inhibitors such as clavulanic acid. ( http://cmr.asm.org/content/18/4/657.full [18.10.2013]) See also: cephalosporin (related) [ IATE:1361346 ]"
- bêta-lactamase à spectre étendu | β-lactamase à spectre étendu | BLSE | β-lactamase à spectre élargi | bêta-lactamase à spectre élargi
- fr
- Definition enzyme produite par certaines bactéries qui inactivent les β-lactamines (p. ex., pénicillines, céphalosporines, carbapénèmes) Reference "Santé publique Ontario, 2013, Annexe A: Dépistage, analyse et surveillance des organismes antibiorésistants (OA), http://www.publichealthontario.ca/fr/eRepository/PIDAC-IPC_Annex_A_Screening_Testing_Surveillance_AROs_2013_FR.pdf [16.3.2015]"
- Comment La β-lactamase à spectre étendu agit sur l'ensemble des céphalosporines, y compris celles de troisième génération telles que le céfotaxime, la ceftriaxone et la ceftazidime, de même que l'aztréonam, un monobactame.