Gaois

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  1. SOCIAL QUESTIONS|health|medical science|immunology
    seicphointe imdhíonachta Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    seicphointe coisctheach Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    immune checkpoint | inhibitory checkpoint
    en
    Definition point in the immune system acting as a brake and involved in- slowing down immune reactions to keep them under control; - helping to keep the immune system from attacking normal “self” cells (preventing autoimmune diseases); - preventing excessive responses to everyday threats (like potential allergens); and - restoring order after a strong immune response to a threat (like a viral or bacterial infection) has been eliminated. Reference "COM-Terminology Coordination, based on: UCIR. 'Checkpoint Blockade' (3.5.2024)"
    Comment Immune checkpoints are signalling pathways.---------------------------------------While checkpoints serve as an important safety mechanism, in some cases, they may slow down desirable immune responses too soon.