Gaois

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2 results

  1. SOCIAL QUESTIONS|health|medical science

    #647024

    IATE #3533538
    measúnacht fótatocsaineachta um iontógáil dhearg neodrach 3T3 Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    tástáil fótatocsaineachta 3T3 NRU Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    3T3 NRU PT | 3T3 Neutral Red Uptake Phototoxicity Assay | 3T3 NRU phototoxicity test
    en
    Definition test used to identify the phototoxic effect of a test substance induced by the combination of test substance and light and is based on the comparison of the cytotoxic effect of a test substance when tested after the exposure and in the absence of exposure to a non-cytotoxic dose of UVA/vis light. Cytotoxicity is expressed as a concentration-dependent reduction of the uptake of the vital dye - Neutral Red. Reference "MB Research Labs. General Background http://3t3nru.mbresearchlabs.com/background.htm [12.4.2011]"
    Comment "The 3T3 NRU PT test was developed and validated in a joint EU/COLIPA project from 1992-1997.In 1996, the 3T3 NRU PT was recommended by OECD as an in vitro approach for the assessment of chemicals phototoxicity potential.In April 2004, the 3T3 NRU PT protocol was finalized and adopted as the OECD 432 protocol, in vitro 3T3 NRU phototoxicity test [ IATE:3529845 ]."
  2. SOCIAL QUESTIONS|health|medical science

    #646498

    IATE #3529845
    scrúdú fótatocsaineachta 3T3 NRU in vitro Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    in vitro 3T3 NRU phototoxicity test
    en
    Definition test used to identify the phototoxic potential of a test substance induced by the excited chemical after exposure to light. The test evaluates photo-cytotoxicity by the relative reduction inviability of cells exposed to the chemical in the presence versus absence of light. Substances identified by this test are likely to be phototoxic in vivo following systemic application and distribution to the skin, or after topical application Reference "Council Regulation (EC) No 440/2008 laying down test methods pursuant to Regulation (EC) No 1907/2006 of the European Parliament and of the Council on the Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH) CELEX:32008R0440/EN"
    test de phototoxicité in vitro 3T3 NRU
    fr