SOCIAL QUESTIONS|health|pharmaceutical industry · INDUSTRY|chemistry
- aigéad sein-dé-ocsacólach Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
- ga
- chenodeoxycholic acid | chenodesoxycholic acid, chenocholic acid | CDCA
- en
- Definition bile acid occurring as a white crystalline substance that is insoluble in water but which is soluble in alcohol and acetic acid, with a melting point of 165-167 °C Reference "COM-EN, based on: Wikipedia > Chenodeoxycholic acid. http://en.wikipedia.org/wiki/Chenodeoxycholic_acid [29.8.2011]"
- Comment Chenodeoxycholic acid is one of the 4 main organic acids synthesized in the liver from cholesterol. This compound, when altered by bacteria in the colon, will result in conversion to its secondary bile acid known as lithocholic acid. Both of these bile acids, in addition to the others, can be conjugated to taurine or glycine. Conjugation, a function carried out by the liver will result in a lowered pKa and therefore, the compounds will remain ionized. These ionized compounds will stay in the gastrointestinal tract until reaching the ileum where they will be reabsorbed. The purpose of this conjugation is to keep the bile acids in the tract until the end to facilitate lipid digestion all the way to the ileum.
- acide chénodésoxycholique
- fr
- Definition "acide biliaire primaire [ IATE:3536264 ], directement issu du catabolisme du cholestérol dans le foie" Reference "COM-FR, d'après: Wikipédia, Acide chénodésoxycholique, http://fr.wikipedia.org/wiki/Acide_ch%C3%A9nod%C3%A9soxycholique [22.10.2012] et Faculté de médecine Pierre & Marie Curie, Partie II - Digestion, Chapitre 8 - La bile, http://www.chups.jussieu.fr/polys/biochimie/DGbioch/POLY.Chp.8.6.html [22.10.2012]"