Gaois

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  1. SCIENCE|natural and applied sciences|life sciences

    #593283

    IATE #3577885
    gabhdóir ianchainéil lioganngheataithe Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    chemically gated ion channel | ligand-gated ion channel receptor | ligand-gated ion channel | ionotropic receptor
    en
    Definition ion channel receptor which has to be bound by a ligand (i.e. a molecule that binds another specific molecule, in some cases, delivering a signal in the process) or a signal molecule for the channel to open its pores [ IATE:1149329/EN ] Reference COM-Terminology Coordination, based on: 1) J.E. Campbell, D. Cohall. 'Chapter 26 - Pharmacodynamics — A Pharmacognosy Perspective. Pharmacognosy Fundamentals'(18.2.2020), Applications and Strategies 2017, Pages 513-525. Academic Press2) Lisa Bartee, Walter Shriner, and Catherine Creech. Principles of Biology: Biology 211, 212, and 213. 'Types of Receptors' (18.2.2020)
    Comment Such specific ligands or signal molecules are hormones, neurotransmitters, or local hormones. Such channels are primarily responsible for impulse initiation = initial depolarization of an excitable cell such as neurons, muscle cells, and gland cells; they can contribute to either depolarization, repolarization or hyperpolarization of a cell, depending on circumstances.