Gaois

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5 results

  1. SCIENCE|natural and applied sciences|life sciences

    #634598

    IATE #1686845
    deisiú DNA trí eisceadh Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    deisiú trí eisceadh Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    Reparatur der DNA durch Exzisionsresynthese
    de
    excision repair | excision repair process | excision and repair
    en
    Definition the single strand repair mechanism of DNA wherein the damaged segment is removed and subsequently replaced through DNA synthesis using the undamaged strand as a template Reference "COM-EN, based on:Hedgehog Signaling Glossary. Excision repair http://groups.molbiosci.northwestern.edu/holmgren/Glossary/Definitions/Def-E/excision_repair.html [1.3.2011]"
    Comment "These mechanisms include:- Base excision repair [ IATE:2109769 ] - Nucleotide excision repair- Mismatch repair [ IATE:1686084 ]"
    réparation de l'ADN par excision-resynthèse
    fr
    Definition système de réparation fidèle de l'ADN qui agit sur la lésion d'un seul brin de l'ADN double brin Reference Dict.de génétique,CILF,1991
  2. SCIENCE|natural and applied sciences|life sciences

    #638083

    IATE #2109769
    deisiú trí eisceadh bunaidh Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    BER | base excision repair
    en
    Definition one of the three excision repair mechanisms that employ all organisms in order to repair their DNA by removing small, non-helix-distorting base lesions from the genome Reference "COM-EN, based on:Wikipedia http://en.wikipedia.org/wiki/Base_excision_repair [1.3.2011]"
    Comment The related nucleotide excision repair pathway repairs bulky helix-distorting lesions. BER is important for removing damaged bases that could otherwise cause mutations by mispairing or lead to breaks in DNA during replication.
  3. SOCIAL QUESTIONS|health|medical science · SCIENCE|natural and applied sciences|life sciences

    #646478

    IATE #3529778
    deisiú fadphaiste Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    deisiú fadphaiste trí eisceadh bunaidh Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    longpatch repair | long-patch repair | long-patch DNA repair | long-patch base-excision repair | long-patch BER | LP-BER
    en
    Definition "base excision repair mechanism [ IATE:2109769 ] involving more than one nucleotide" Reference "COM-EN, based on: Ulrike Sattler, Philippe Frit, Bernard Salles, and Patrick Calsou. Long-patch DNA repair synthesis during base excision repair in mammalian cells. EMBO Rep. 2003 April; 4(4): 363–367 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1319152/ [1.3.2011]"
    Comment "See also short patch repair IATE:1584279"
    réparation de longues séquences
    fr
  4. SOCIAL QUESTIONS|health|medical science

    #602558

    IATE #161281
    deisiú trí eisceadh núicléitídí Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    NER | nucleotide excision repair
    en
    Definition repair pathway, involved in the removal of a variety of bulky DNA lesions Reference "Leon H.F. Mullenders, Anne Stary and Alain Sarasin. Nucleotide excision repair. Atlas of Genetics and Cytogenetics in Oncology and Haematology http://atlasgeneticsoncology.org/Deep/ExcisRepairID20014.html [10.2.2012]"
    Comment NER is a complex process in which basically the following steps can be distinguished:(i) recognition of a DNA lesion;(ii) separation of the double helix at the DNA lesion site;(iii) single strand incision at both sides of the lesion;(iv) excision of the lesion-containing single stranded DNA fragment;(v) DNA repair synthesis to replace the gap and(vi) ligation of the remaining single stranded nick.
    réparation par excision de nucléotides | REN
    fr
    Definition système de réparation versatile qui permet d'éliminer une grande variété de dommages de l'ADN Reference "COM-FR d'après Test fonctionnel de mesure des activités enzymatiques de réparation de l’ADN par excision resynthèse sur support miniaturisé: mise au point et applications, thèse présentée par Jean-François Millau (2006), Université Joseph-Fourier de Grenoble, http://tel.archives-ouvertes.fr/docs/00/12/68/58/PDF/These_Millau.pdf [12.2.2014]"
    Comment "On peut décomposer ce mécanisme en cinq étapes: la reconnaissance du dommage, l’incision du brin d’ADN contenant le dommage, son excision, la re-synthèse du brin excisé, et enfin la ligation du brin néoformé. Voir: Test fonctionnel de mesure des activités enzymatiques de réparation de l’ADN par excision resynthèse sur support miniaturisé: mise au point et applications, thèse présentée par Jean-François Millau (2006), Université Joseph-Fourier de Grenoble, http://tel.archives-ouvertes.fr/docs/00/12/68/58/PDF/These_Millau.pdf [12.2.2014]"
  5. SCIENCE|natural and applied sciences|life sciences

    #631893

    IATE #1584279
    deisiú gearrphaiste Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    Kurzstück-Reparatur
    de
    short patch repair | shortpatch repair | short-patch DNA repair | short-patch base excision repair | short-patch BER | SP-BER
    en
    Definition "base excision repair mechanism [ IATE:2109769 ] involving only one nucleotide" Reference "COM-EN, based on:Ulrike Sattler, Philippe Frit, Bernard Salles, and Patrick Calsou. Long-patch DNA repair synthesis during base excision repair in mammalian cells. EMBO Rep. 2003 April; 4(4): 363–367 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1319152/ [1.3.2011]"
    Comment "See also:- long-patch repair IATE:3529778 - excision repair IATE:1686845"