Gaois

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  1. PRODUCTION, TECHNOLOGY AND RESEARCH|technology and technical regulations|biotechnology

    #664657

    IATE #3592534
    modhnú nár bhain an sprioc amach Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    Context 'Maidir le substaintí a bhfuil sé beartaithe iad a chomhtháthú sa ghéanóm nó an géanóm a mhodhnú leo, déanfar tástálacha chun meastóireacht a dhéanamh ar an riosca de mhodhnuithe nár bhain an sprioc amach agus/nó de shó-ghineas ionlocach.' Reference "Rialachán Tarmligthe (AE) 2021/805 lena leasaítear Iarscríbhinn II a ghabhann le Rialachán (AE) 2019/6 ó Pharlaimint na hEorpa agus ón gComhairle, CELEX:32021R0805/GA"
    modhnú seachsprice Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    Off-Target-Veränderung | Off-Target-Effekt
    de
    Definition ungewollte Veränderungen der DNA an Nicht-Zielsequenzen Reference "FGU - Fachstelle Genetik und Umwelt: Hintergrund: CRISPR/Cas (Risiken) (1.6.2021)"
    off-target change | off-target edit | off-target mutation | off-target modification
    en
    Definition unintended, non-specific mutation occurring at a site with sequence similarity to the targeted edit region Reference "Nathaniel Graham, Gunvant B. Patil, David M. Bubeck, Raymond C. Dobert, Kevin C. Glenn, Annie T. Gutsche, Sandeep Kumar, John A. Lindbo, Luis Maas, Gregory D. May, Miguel E. Vega-Sanchez, Robert M. Stupar, Peter L. Morrell. 'Plant Genome Editing and the Relevance of Off-Target Changes' (26.1.2021). Plant Physiology Aug 2020, 183 (4) 1453-1471; DOI: 10.1104/pp.19.01194"
    mutation hors cible | modification hors cible | changement hors cible
    fr
    Definition mutation se produisant en dehors de la zone initialement ciblée par l'édition génomique, sur un site dont la séquence est similaire Reference "COM-FR, d'après:- Inserm - La science pour la santé, Information en santé, Dossiers d'information > Édition génomique (11.3.2021)- Pourquoi docteur - Comprendre pour agir > Question d'actu > Innovation, 5 décembre 2019, «Mutations génétiques : inquiétudes pour les jumelles «CRISPR» en Chine» (11.3.2021)"