SOCIAL QUESTIONS|health|medical science
- scagthástáil gaolta Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
- ga
- familial | cascade screening | family screening | cascade genetic screening | family-based cascade screening | family cascade screening
- en
- Definition systematic screening of the relatives of patients affected by genetic disordersCascade screening is used to identify asymptomatic individuals who are at risk of developing a disease because they have an affected relative. Reverse cascade screening ( IATE:2250825 ) identifies the asymptomatic individual first and uses this information to identify undiagnosed affected relatives. Reference Based on: Guido de Wert, Cascade Screening: Whose information is it anyway? European Journal of Human Genetics (2005) 13, 397–398. http://www.nature.com/ejhg/journal/v13/n4/full/5201373a.html [15.9.2008] & E Cadet, D Capron, M Gallet, M-L Omanga-Léké, H Boutignon, C Julier, K J H Robson and J Rochette. J. Med. Genet. Reverse cascade screening of newborns for hereditary haemochromatosis: a model for other late onset diseases? J. Med. Genet. 2005;42;390-395 http://jmg.bmj.com/cgi/reprint/42/5/390.pdf [15.9.2008]
- Comment See also: M. Krawczak, D. N. Cooper, J. Schmidtke. Estimating the Efficacy and Efficiency of Cascade Genetic Screening, American Journal of Human Genetics, Volume 69, Issue 2, August 2001, Pages 361-370 http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B8JDD-4R17R7X-D&_user=586419&_rdoc=1&_fmt=&_orig=search&_sort=d&view=c&_version=1&_urlVersion=0&_userid=586419&md5=844be92903f5e87e780af7e8c275d3a6 [15.9.2008]