Gaois

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15 results

  1. SCIENCE|natural and applied sciences|life sciences
    aigéad núicléasach Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    Nucleinsäure
    de
    nucleic acid
    en
    Definition "either of two types of macromolecule (DNA [ IATE:1073333 ] or RNA [ IATE:1073359 ]) formed by polymerisation of nucleotides [ IATE:1073318 ]" Reference Coombs
    Comment Nucleic acids are found in all living cells and contain the information (genetic code) for the transfer of genetic information from one generation to the next, as well as for the expression of this information through protein synthesis.
    acide nucléique
    fr
    Definition Enchaînement macromoléculaire dont la fonction est de conserver et de transférer l'information génétique.Il y a deux acides nucléiques fondamentaux:l'acide désoxyribonucléique(ADN)et l'acide ribonucléique(ARN) Reference Lehninger,p.305
  2. SOCIAL QUESTIONS|health|medical science · SCIENCE|natural and applied sciences|life sciences|biology
    measúnacht hibridithe aigéid núicléasaigh neamh-aimplithe Reference "Faofa ag an gCoiste Téarmaíochta, www.tearma.ie ;Faomhadh an téarma seo mar chuid de Thionscadal Lex"
    ga
    Sondentest an nicht amplifizierter Nukleinsäure | Nukleinsäurehybridisierungstest
    de
    non-amplified nucleic acid probe test | non-amplified nucleic acid hybridisation assay | NAH assay | nucleic acid hybridization assay | hybridisation assay | non-amplified nucleic acid hybridization assay | hybridization assay
    en
    Definition test used to detect a particular nucleic acid sequence, usually to identify a particular species or subspecies of organism (a virus or bacteria that acts as a pathogen in blood, tissue, urine, etc.), without amplifying the genetic material Reference "COM-EN, based on:Nucleic acid test (24.11.2020), Wikipedia"
    Comment This allows an earlier diagnosis of a disease than tests that detect antigens and/or antibodies, which require time to start appearing in the bloodstream.
    détection par hybridation moléculaire sans amplification | mise en évidence au moyen d'une sonde d'acide nucléique non amplifié | sonde d'acide nucléique non amplifié | hybridation moléculaire sans amplification
    fr
    Definition test basé sur une technique permettant de mettre en évidence une séquence d'acide nucléique spécifique à l’intérieur d’une cellule ou d’un tissu sans amplification de cette séquence Reference "COM-FR, d'après:- Le Manuel MSD - Version pour professionnels de la santé, juin 2018, Méthodes basées sur les acides nucléiques d'identification des maladies infectieuses (8.12.2020)- Futura Santé > Définitions > Hybridation moléculaire (8.12.2020)- Bioalternatives > HYBRIDATION in situ: VISUALISATION ET QUANTIFICATION DE L'EXPRESSION DE GENES (8.12.2020)"
    Comment Les techniques qui ciblent des séquences d'acides nucléiques mais qui ne nécessitent pas d'amplification de ces séquences sont généralement adaptées aux situations dans lesquelles les microrganismes ont été d'abord mis en culture ou sont présents à de fortes concentrations dans le prélèvement (p. ex., pharyngite due à Streptococcus du groupe A, infections génitales dues à Chlamydia trachomatis et Neisseria gonorrhoeae).
  3. SCIENCE|natural and applied sciences|life sciences|biology
    teicníc aimpliúcháin aigéid núicléasaigh Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    NAT | Nukleinsäuren-Amplifikationstechnik
    de
    Comment Term defined --
    nucleic acid amplification technique | nucleic amplification technique | nucleic acid amplification technology | NAT technique | NAAT | NAT
    en
    Definition technique used to detect a particular nucleic acid sequence and thus usually to detect and identify a particular species or subspecies of organism, often a virus or bacteria that acts as a pathogen in blood, tissue, urine, etc. that includes a step that amplifies the genetic material Reference "COM-Terminology Coordination, based on:Wikipedia > Nucleic acid test (21.8.2020)"
    NAT | technique d'amplification des acides nucléiques
    fr
    Definition tests de détection et/ou de quantification d’acides nucléiques, soit par amplification d’une séquence cible ou d’un signal, soit par hybridation Reference "Décision de la Commission du 3 février 2009 modifiant la décision 2002/364/CE portant spécifications techniques communes des dispositifs médicaux de diagnostic in vitro , JO L 39 du 10.2.2009 , p. 36 , http://eur-lex.europa.eu/LexUriServ/LexUriServ.do?uri=OJ:L:2009:039:0034:0049:FR:PDF"
    Comment Term defined --
  4. SCIENCE|natural and applied sciences|life sciences
    tástáil aimpliúcháin aigéid núicléasaigh Reference "'Tuarascáil Bhliantúil 2007,' an Oifig Náisiúnta Haemafhaireachais, https://www.giveblood.ie/Clinical-Services/Haemovigilance/Publications/Tuarasc%C3%A1il_Bhliant%C3%BAil_2007.pdf [12.4.2021] ;Faomhadh an téarma seo mar chuid de Thionscadal Lex"
    ga
    nucleic acid amplification test | NAAT | NAAT test | NAATs
    en
    Definition "test that uses nucleic acid amplification technique" Reference "COM-Terminology Coordination, based on:Wikipedia > Nucleic acid test (21.8.2020)"
    test d’amplification des acides nucléiques | test TAAN
    fr
    Definition "test d’amplification des acides nucléiques moléculaires, comme les techniques de réaction en chaîne par polymérase après transcription inverse (RT-PCR), d’amplification isotherme induite par boucle (LAMP) et d’amplification induite par la transcription (TMA), utilisé pour détecter la présence de l’acide ribonucléique (ARN) du SARS-CoV-2" Reference "Règlement (UE) 2021/953 relatif à un cadre pour la délivrance, la vérification et l’acceptation de certificats COVID-19 interopérables de vaccination, de test et de rétablissement (certificat COVID numérique de l’UE) afin de faciliter la libre circulation pendant la pandémie de COVID-19"
  5. SCIENCE|natural and applied sciences|life sciences|biology
    hibridiú aigéid núicléasaigh Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    ainéaladh Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    hibridiú Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    Context 'Is féidir leis an mbagairt ar an mbithéagsúlacht agus ar na seirbhísí gaolmhara éiceachórais a thagann ó speicis choimhthíocha ionracha a bheith i bhfoirmeacha éagsúla, lena n-áirítear tionchair mhóra ar speicis dhúchasacha agus struchtúr agus feidhm éiceachóras trí athrú gnáthóg, creachóireacht, iomaíocht, tarchur galar, ionadú na speiceas dúchasach ar fud céatadáin shuntasaigh raoin agus trí éifeachtaí géiniteacha trí hibridiú.' Reference "Rialachán (AE) Uimh. 1143/2014 maidir le tabhairt isteach agus leathadh speiceas coimhthíoch ionrach a chosc agus a bhainistiú, CELEX:32014R1143/GA"
    athnádúrúchán Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    Hybridisierung der Nucleinsäuren | Annealing | Renaturierung | Reannealing
    de
    Definition In der Molekularbiologie, versteht man unter diesem Begriff die Hybridisierung zweier komplementärer Nucleinsäure-Stränge zu einem Doppelstrang; durch Hybridisierung prüft man, ob die Basenfolge korrekt ist. ; Generell die Rückbildung doppelsträngiger Nucleinsäure-Bereiche aus zwei einzelsträngigen Nucleinsäure-Strängen. ; Übergang eines Proteins oder einer Nucleinsäure vom denaturierten Zustand in die native Konfiguration Reference Römpp ; Ibelgaufts H.,Gentechnologie von A bis Z,VCH,Weinheim ; Lex.Biochemie
    nucleic acid hybridisation | NAH | hybridisation | annealing | renaturation | nucleic acid hybridization | hybridization
    en
    Definition formation of hybrid double‐stranded nucleic acid molecules by the slow cooling of a mixture of denatured, single‐stranded nucleic acids Reference "'annealing' (27.8.2020), Richard Cammack, Teresa Atwood, Peter Campbell, Howard Parish, Anthony Smith, Frank Vella, and John Stirling (Eds.), Oxford Dictionary of Biochemistry and Molecular Biology (2 ed.), Oxford University Press, 2008."
    Comment "Hybridisation can take place between complementary strands of both DNA and RNA to produce duplex DNA, duplex RNA or duplex DNA-RNA hybrid molecules.See also:- annealing (of primers)"
    hybridisation moléculaire | annelage | renaturation | renaturation d'acide nucléique | hybridation des acides nucléiques
    fr
    Definition Méthode de diagnostic où deux séquences de nucléotides interagissent l'une sur l'autre, en s'hybridant au niveau de ces séquences ; hybridation d'un oligonucléotide synthétique à un acide nucléique simple brin ; Réapparition de la structure d'une macromolécule après que celle-ci a subi un traitement ménagé qui l'a déformée sans cependant l'altérer définitivement. En retrouvant sa forme, la molécule retrouve la fonction qu'elle avait perdue en subissant sa dénaturation ; réassociation, après dénaturation, de simples brins d'ADN ou d'ARN complémentaires Reference Biofutur 6/85,p.17 ; arrêté du 14/09/90 relatif à la terminologie du génie génétique,JORF 26/09/90 ; Dict.de Biologie ; arrêté du 14/09/90 relatif à la terminologie du génie génétique,JORF 26/09/90
  6. SCIENCE|natural and applied sciences|life sciences|biology
    taiscéalaí hibridiúcháin Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    tóireadóir hibridiúcháin Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    Hybridationssonde | Hybridisierungsprobe
    de
    hybridisation probe | hybridization probe | nucleic acid probe
    en
    Definition single stranded DNA or an RNA with a strong affinity towards a specific DNA or RNA target sequence tagged with a label that can be detected Reference "COM-Terminology Coordination, based on: Arun Kumar. 'What are the Differences Between DNA and RNA Probes?' (24.3.2021)"
    Comment In theory, any nucleic acid can be used as a probe provided it can be labeled to permit identification and quantitation of the hybrid molecules formed between the probe and sequence to be identified.
    sonde d'hybridation
    fr
    Definition Sonde d'ADN utilisée pour le repérage de gènes particuliers, pour la recherche d'oncogènes viraux et de leurs homologues cellulaires Reference Biofutur 5/83 p.7
  7. SCIENCE|natural and applied sciences|life sciences|biology
    macasamhlú aigéid núicléasaigh Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    nucleic acid replication
    en
    Definition generation of a copy of a nucleic acid Reference "COM-Terminology Coordination, based on: - National Human Genome Research Institute. 'DNA Replication' (19.10.2021)- Wikipedia > Viral replication (19.10.2021)"
  8. SCIENCE|natural and applied sciences|life sciences
    teicníc an aigéid núicléasaigh Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    nucleic acid technique
    en
    Definition any technique that modifies, amplifies, detects, discriminates and sequences nucleic acids Reference "Carl T. Wittwer, G. Mike Makrigiorgos. '4 - Nucleic Acid Techniques' (21.8.2020). In: Principles and Applications of Molecular Diagnostics 2018, Pages 47-86"
    Comment Nucleic acids are usually first purified and then amplified to provide enough NA to be easily detected and analyzed. However, not all techniques require NA purification or amplification before analysis.
  9. SCIENCE|natural and applied sciences|life sciences
    tástáil aigéid núicléasaigh Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    NAT Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    nucleic acid test | NAT | NATs | nucleic acid testing
    en
    Definition any biochemical technique that directly detects the genetic material of the infecting organism or virus Reference "COM-EN, based on:Wikipedia > Nucleic acid test (21.8.2020)"
    Comment "There are multiple methods that fall in this group, including:1) Methods based on the Polymerase chain reaction. These tests use a primer to rapidly make copies of the genetic material. a) A reverse transcriptase PCR (RT-PCR) is used for HIV and other RNA viruses.b) Transcription mediated amplification uses a slightly different molecular method than PCR but has the same basic principle.2) Branched DNA (quantiplex bDNA) tests use a molecule that links to the specific genetic material.3) Ligase chain reaction."
  10. SOCIAL QUESTIONS|health|pharmaceutical industry|pharmaceutical product|vaccine · SOCIAL QUESTIONS|health|pharmaceutical industry · PRODUCTION, TECHNOLOGY AND RESEARCH|technology and technical regulations|biotechnology
    vacsaín aigéid núicléasaigh Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    vacsaín ghéiniteach Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    nukleinsäurebasierter Impfstoff | genbasierter Impfstoff
    de
    nucleic acid vaccine | genetic vaccine
    en
    Definition vaccine consisting in genetically engineered DNA (as a plasmid) or RNA (as mRNA) which employs the host's transcriptional and translational machinery to produce the desired gene product that can then be recognized by the immune system Reference "COM-Terminology Coordination, based on:Creative Biolabs. 'DNA and RNA Vaccine Design' (11.6.2020)"
    Comment The term is often used as a synonym of the narrower term DNA vaccine, because research on mRNA vaccines is more recent.
    vaccin à base d'acide nucléique | vaccin à acide nucléique | vaccin génétique
    fr
    Definition "vaccin qui consiste en l'introduction dans l'organisme d'une partie du matériel génétique de l'agent pathogène, dont on prélève la fraction d'ADN ou d'ARNm codant pour la protéine susceptible de déclencher une réaction immunitaire protectrice (antigène)" Reference "COM-FR, d'après:- Site de Sénat > Rapports > Rapports d'information (1e juiller 2020) > 1.2.3. Les nouveaux vaccins > 1.2.3.2. La vaccination génique (1.7.2020)- National Geographic > Sciences (4 juin 2020) > COVID-19 : un vaccin en phase de test sur l'Homme (1.7.2020)"
    Comment "Les vaccins à ADN sont un type de vaccin à base d'acide nucléique."
  11. PRODUCTION, TECHNOLOGY AND RESEARCH|technology and technical regulations|biotechnology · SCIENCE|natural and applied sciences|life sciences|biology
    aigéad núicléasach athchuingreach Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    Context 'Is táirgí íocshláinte tréidliachta bitheolaíocha iad táirgí géinteiripe ina bhfuil substaint ghníomhach ina bhfuil aigéad núicléasach athchuingreach, nó atá comhdhéanta d’aigéad núicléasach athchuingreach, a úsáidtear in ainmhithe nó a thugtar dóibh chun seicheamh géiniteach a rialáil, a dheisiú, a ionadú, cur leis, nó é a scriosadh.' Reference "Rialachán Tarmligthe (AE) 2021/805 lena leasaítear Iarscríbhinn II a ghabhann le Rialachán (AE) 2019/6 ó Pharlaimint na hEorpa agus ón gComhairle, CELEX:32021R0805/GA"
    rekombinante Nukleinsäure
    de
    recombinant nucleic acid
    en
    Definition molecule constructed by joining nucleic acid molecules and which can replicate in a living cell Reference "COM-Terminology Coordination, based on: Jacqueline Corrigan-Curay, 'Synthetic Biology and the NIH Guidelines for Experiments Involving Recombinant DNA Molecules' (1.2.2021)"
    Comment They can occur naturally as a result of a genetic recombination or be the result of a biotechology process
    acide nucléique recombinant
    fr
  12. PRODUCTION, TECHNOLOGY AND RESEARCH|technology and technical regulations|biotechnology
    seicheamh aigéad núicléasach athchuingreach Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    recombinant nucleic acid sequence
    en
    Definition nucleic acid sequence either constructed outside living cells by joining natural or synthetic DNA segments to DNA molecules that can replicate in a living cell, or that result from the replication of those described above Reference "COM-Terminology Coordination, based on: Jacqueline Corrigan-Curay, 'Synthetic Biology and the NIH Guidelines for Experiments Involving Recombinant DNA Molecules' (1.2.2021)"
  13. SCIENCE|natural and applied sciences|life sciences|biology
    aigéad núicléasach satailíteach Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    satellite nucleic acid
    en
    Definition "subviral agent that encodes either non-structural proteins, or no proteins at all, and is encapsidated by the coat protein of helper viruses" Reference "COM-Terminology Coordination, based on: ICTV. ICTV 9th Report (2011). Subviral Agents (2011) Subviral Agents New '3 - Satellites and Other Virus-dependent Nucleic Acids' (23.11.2020)"
  14. SCIENCE|natural and applied sciences|life sciences|biology
    aigéad núicléasach satailíteach Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    satellite-like nucleic acid
    en
    Definition "agent resembling a satellite because it does not encode a replicase but differs because its encodes a function necessary for the biological success of the associated virus" Reference "ICTV. ICTV 9th Report (2011). Subviral Agents (2011) Subviral Agents New '3 - Satellites and Other Virus-dependent Nucleic Acids' (23.11.2020)"
  15. SCIENCE|natural and applied sciences|life sciences|biology · PRODUCTION, TECHNOLOGY AND RESEARCH|technology and technical regulations|biotechnology
    hibridiú pas sholadaigh Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    hibridiú dromchla Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    hibridiú aigéid núicléasaigh pas sholadaigh Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    solid-phase hybridisation | solid-phase hybridization | surface hybridization | solid phase nucleic acid hybridization | solid phase nucleic acid hybridisation
    en
    Definition process of recognition between nucleic acid probes immobilised on a solid surface and complementary targets in a solution Reference "COM-Terminology Coordination, based on: - Tomáš Špringer, Hana Šípová, Hana Vaisocherová, Josef Štěpánek, Jiří Homola, 'Shielding effect of monovalent and divalent cations on solid-phase DNA hybridization: surface plasmon resonance biosensor study' (24.3.2021), Nucleic Acids Research, Volume 38, Issue 20, 1 November 2010, Pages 7343–7351- Ping Gong and Rastislav Levicky. 'DNA surface hybridization regimes' (24.3.2021).Proceedings of the National Academy of Sciences Apr 2008, 105 (14) 5301-5306; DOI: 10.1073/pnas.0709416105"