SOCIAL QUESTIONS|health|medical science
- iditíopa Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
- ga
- antaigin iditíopach Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
- ga
- Idiotop
- de
- Definition einzelne Antigendeterminante Reference Wörterbuch Allergologie und Immunologie, Springer, Wien, 2005, http://www.springerlink.com/content/g63264h5m3j73308/ (28.8.2009)
- idiotypic antigen | idiotypic antigenic determinant | idiotope
- en
- Definition antigenic determinant (epitope) [ IATE:1073785 ] which is unique to a single clone of cells and is made up of amino acids within the variable (V) region of an antibody [ IATE:1073776 ] or T-cell receptor [ IATE:1221832 ] that reacts with an anti-idiotype antibody [ IATE:1073784 ] Reference IUPAC Glossary of Terms used in Immunotoxicology http://old.iupac.org/reports/provisional/abstract11/templeton_prs.pdf [20.9.2011]
- Comment The idiotope forms part of the antigen [ IATE:1503455 ] binding site. Any single immunoglobulin [ IATE:1224959 ] may have more than one idiotope. Idiotopes are also associated with the antigen binding sites of T-cell receptors [ IATE:1221832 ] . They are the epitopes [ IATE:1073785 ] to which an anti-idiotype antibody [ IATE:1073784 ] or T-cell [ IATE:1431862 ] binds.The anti-idiotopic region of the anti-idiotype antibody [ IATE:1073784 ] may mimic the antigenic determinant (epitope) [ IATE:1073785 ] binding characteristics of the antigen [ IATE:1503455 ] without sharing any sequence homology.
- idiotope
- fr
- Definition déterminant antigénique de la région V des immunoglobulines Reference Dict.des Sciences Pharmaceutiques et Biologiques,Académie Nationale de Pharmacie,éd.Louis Pariente,vol.2,p.290