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- gaschill aosach Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
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- gaschill shómach Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
- ga
- adult tissue stem cell | tissue stem cell | TSC | TSCs | adult stem cell | ASC | ASCs | somatic stem cell
- en
- Definition relatively rare undifferentiated or partially differentiated, post-embryonic or postnatal plant or animal cell found in many organs and differentiated tissues that has a limited capacity to proliferate, self-renew, and produce one or more types of differentiated progeny Reference "COM-EN, based on:- 'stem cells' in 'A Dictionary of Genetics'. Robert C. King, William D. Stansfield and Pamela K. Mulligan. Oxford University Press (OUP), 2007. Oxford Reference Online. OUP. DGT, http://www.oxfordreference.com/views/ENTRY.html?subview=Main&entry=t224.e6189 [3.8.2011]- 'Somatic (adult) stem cells' in 'Glossary', US National Institutes of Health Stem Cell Information, http://stemcells.nih.gov/StemCells/Templates/StemCellContentPage.aspx?NRMODE=Published&NRNODEGUID=%7b3C35BAB6-0FE6-4C4E-95F2-2CB61B58D96D%7d&NRORIGINALURL=%2finfo%2fglossary%2easp&NRCACHEHINT=NoModifyGuest#somaticsc [3.8.2011]"
- Comment "Such cells vary in their differentiation capacity, but it is usually limited to cell types in the organ of origin. Through in vivo and in vitro manipulations, TSCs have been identified in a variety of tissues (e.g. bone marrow, central nervous system, the epidermis, intestinal epithelium, skeletal muscle, the germ line, and shoot and root apical meristems), where they serve to replace cells that die, are lost due to injury, or are continually depleted during the life of the organism. TSCs differ from ESCs in that during normal development TSCs are more limited in their in vivo developmental potential, and their cell division gives rise to one daughter cell that acts as a stem cell and another that produces differentiated progeny. The stem cell state and the developmental capacity of the daughter cells is influenced by signals from the surrounding environment, and TSCs show plasticity in choosing their course of differentiation when their microenvironment is altered. Mutations that affect stem cell fate have been identified in both plants and animals.See also:stem cell [ IATE:1077058 ]embryonic stem cell [ IATE:1036294 ]"