ECONOMICS|economic analysis|statistics · SOCIAL QUESTIONS|health|pharmaceutical industry
- stóinseacht Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
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- Robustheit
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- Definition Unempfindlichkeit gegenüber Anwendungsvoraussetzungen Reference "Gabler Wirtschaftslexikon, Online-Ausgabe, s. v. ""robuste Statistik"", http://wirtschaftslexikon.gabler.de/Definition/robuste-statistik.html (3.7.2012)"
- robustness
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- Definition sensitivity of the overall conclusions to various limitations of the data, assumptions, and analytic approaches to data analysis Reference "European Medicines Agency. 'ICH Topic E 9 Statistical Principles for Clinical Trials. Step 5. NOTE FOR GUIDANCE ON STATISTICAL PRINCIPLES FOR CLINICAL TRIALS' (13.4.2022) (CPMP/ICH/363/96)"
- Comment "1) Many test procedures involving probability levels depend for their exactitude on assumptions concerning the generating mechanism, e.g.that the parent variation is normal (Gaussian). If the inferences are little affected by departure from those assumptions, e.g. if the significance points of a test vary little if the population departs quite substantially from the normality the test on the inferences are said to be robust. In a rather more general sense, a statistical procedure is described as robust if it is not very sensitive to departure from the assumptions on which it depends.2) In a clinical trial setting, robustness implies that the treatment effect and primary conclusions of the trial are not substantially affected when analyses are carried out based on alternative assumptions or analytic approaches. The interpretation of statistical measures of uncertainty of the treatment effect and treatment comparisons should involve consideration of the potential contribution of bias to the p-value, confidence interval, or inference."
- solidité | robustesse
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