SOCIAL QUESTIONS|health|medical science|immunology · SCIENCE|natural and applied sciences|life sciences|biology
- géin C Reference "Faofa ag an gCoiste Téarmaíochta, www.tearma.ie Faomhadh an téarma seo mar chuid de Thionscadal Lex"
- ga
- géin thairiseach Reference "Faofa ag an gCoiste Téarmaíochta, www.tearma.ie Faomhadh an téarma seo mar chuid de Thionscadal Lex"
- ga
- C-gene | constant region gene | constant gene
- en
- Definition "gene that codes for the constant regions of a particular class of immunoglobulins" Reference "'C-gene' (1.10.2020). Collins Dictionary of Biology, 3rd ed. © W. G. Hale, V. A. Saunders, J. P. Margham 2005"
- Comment "1) A unique capacity of B-cells is to initiate rearrangement of dispersed gene segments in order to assemble a new, intact immunoglobulin gene. The V, D, and J segments rearrange to form the antigen binding variable domain of the final immunoglobulin molecule. The V (variable) gene segments encode the bulk of the variable region while the D (diversity) and J (joining) segments form a link to the C (constant) region and form a hypervariable region which contributes to antigen specificity of the antibody molecule. When successfully rearranged, the segments encode a novel antibody molecule.2) The loci encoding immunoglobulins have a unique structure.- composed of ""gene segments""- The heavy chain locus has multiple V (variable) segments, multiple D (diversity) segments, multiple J (joining) segments and multiple C (constant) segments.During maturation, one of each V, D and J segment is randomly “chosen” and used to encode the final antibody molecule."
- gène constant | gène C
- fr
- Definition gène codant le domaine constant Reference Pour la Science,novembre 1993