SCIENCE|natural and applied sciences|life sciences|biology · PRODUCTION, TECHNOLOGY AND RESEARCH|technology and technical regulations|biotechnology
- inleagan géine Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
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- gene knock-in | gene KI
- en
- Definition genetic engineering method that involves the one-for-one substitution of DNA sequence information in a genetic locus or the insertion of sequence information not found within the locus Reference "Wikipedia > Gene knock-in (13.4.2021)"
- Comment "The difference between knock-in technology and traditional transgenic techniques is that a knock-in involves a gene inserted into a specific locus, and is thus a ""targeted"" insertion. It is the opposite of gene knockout. A common use of knock-in technology is for the creation of disease models. It is a technique by which scientific investigators may study the function of the regulatory machinery (e.g. promoters) that governs the expression of the natural gene being replaced. This is accomplished by observing the new phenotype of the organism in question."
- knock-in
- fr