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  1. SCIENCE|natural and applied sciences|life sciences|biology · PRODUCTION, TECHNOLOGY AND RESEARCH|technology and technical regulations|biotechnology
    inleagan géine Tagairt Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    gene knock-in | gene KI
    en
    Sainmhíniú genetic engineering method that involves the one-for-one substitution of DNA sequence information in a genetic locus or the insertion of sequence information not found within the locus Tagairt "Wikipedia > Gene knock-in (13.4.2021)"
    Nóta "The difference between knock-in technology and traditional transgenic techniques is that a knock-in involves a gene inserted into a specific locus, and is thus a ""targeted"" insertion. It is the opposite of gene knockout. A common use of knock-in technology is for the creation of disease models. It is a technique by which scientific investigators may study the function of the regulatory machinery (e.g. promoters) that governs the expression of the natural gene being replaced. This is accomplished by observing the new phenotype of the organism in question."
    knock-in
    fr