Gaois

This is a static copy of data that is exported from IATE on an occasional basis. It should not be assumed that information provided about an entry here will always correspond to the current version of the entry in IATE. That current version can be checked by clicking on the link on the upper right hand side of each entry. More information »

3 results

  1. SCIENCE|natural and applied sciences|life sciences|biology

    #665656

    IATE #3599595
    spícephróitéin réamhleá Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    pre-fusion spike protein | pre-fusion S protein | prefusion spike protein | prefusion S protein
    en
    Definition "spike protein of SARS-CoV-2 in its conformation before fusion of the virus and host cell membranes" Reference "COM-Terminology Coordination, based on: Proteopedia. 'SARS-CoV-2 spike protein fusion transformation' (18.6.2021)"
  2. SOCIAL QUESTIONS|health|pharmaceutical industry|pharmaceutical product|vaccine

    #665658

    IATE #3599598
    vacsaín nanacháithníní spícephróitéine athchuingreach SARS-CoV-2 Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    SARS-CoV-2 recombinant spike protein nanoparticle vaccine
    en
    Definition recombinant severe acute respiratory syndrome coronavirus 2 (rSARS-CoV-2) nanoparticle vaccine composed of trimeric full-length SARS-CoV-2 spike glycoproteins and Matrix-M1 adjuvant Reference "Cheryl Keech, M.D., Ph.D., Gary Albert, M.S., Iksung Cho, M.S., Andreana Robertson, M.S., Patricia Reed, B.S., Susan Neal, Joyce S. Plested, Ph.D., Mingzhu Zhu, Ph.D., Shane Cloney-Clark, B.S., Haixia Zhou, Ph.D., Gale Smith, Ph.D., Nita Patel, M.S., Matthew B. Frieman, Ph.D., Robert E. Haupt, M.S., James Logue, B.A., Marisa McGrath, B.A., Stuart Weston, Ph.D., Pedro A. Piedra, M.D., Chinar Desai, B.S., Kathleen Callahan, M.S., Maggie Lewis, M.S., Patricia Price-Abbott, M.S., Neil Formica, M.B., B.S., Vivek Shinde, M.D., Louis Fries, M.D., Jason D. Lickliter, M.B., B.S., Ph.D., Paul Griffin, M.D., Bethanie Wilkinson, Ph.D., and Gregory M. Glenn, M.D., 'Phase 1–2 Trial of a SARS-CoV-2 Recombinant Spike Protein Nanoparticle Vaccine' (18.6.2021), New England Journal of Medicine 2020; 383:2320-2332"
    NVX-CoV2373
    mul
  3. SOCIAL QUESTIONS|health|medical science · SCIENCE|natural and applied sciences|life sciences|biology

    #633908

    IATE #1661603
    próitéin spíce víreasach Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    spícephróitéin Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    S-próitéin Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    virales Spike-Protein | Spike-Protein | S-Protein
    de
    viral spike protein | spike protein | spike glycoprotein | S-protein
    en
    Definition multifunctional molecular machine that mediates coronavirus entry into host cells Reference "COM-Terminology Coordination, based on: Fang Li. 'Structure, Function, and Evolution of Coronavirus Spike Proteins' (18.3.2020). Annual Review of Virology Vol. 3:237-261 (Volume publication date September 2016) First published online as a Review in Advance on August 25, 2016"
    Comment It first binds to a receptor on the host cell surface through its S1 subunit and then fuses viral and host membranes through its S2 subunit. Two domains in S1 from different coronaviruses recognize a variety of host receptors, leading to viral attachment. The spike protein exists in two structurally distinct conformations, prefusion and postfusion. The transition from prefusion to postfusion conformation of the spike protein must be triggered, leading to membrane fusion
    protéine spike | protéine S
    fr
    Definition protéine virale ancrée dans l'enveloppe virale d'un virus jouant un rôle-clé dans l’entrée dudit virus dans sa cellule-cible Reference "COM-FR, d'après:Serveur TEL - Thèses en ligne, Thèse de doctorat en Virologie, A. Bonnin, Médecine humaine et pathologie, Université du Droit et de la Santé - Lille II (2018), Caractérisation de la protéine S du coronavirus humain 229E (30.4.2020)"
    Comment "Trois protéines virales sont ancrées dans l'enveloppe virale du coronavirus humain 229E: la protéine spike (S), la protéine de membrane (M) et la protéine d’enveloppe (E).La protéine spike (S) est constituée de deux domaines:- le domaine S1, responsable de la liaison du virus à son récepteur;- le domaine S2, responsable de la fusion de l’enveloppe virale avec une membrane cellulaire.Dans le cas du coronavirus humain, la protéine S joue un rôle important dans l'entrée virale."