Gaois

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4 results

  1. SOCIAL QUESTIONS|health|medical science · SCIENCE|natural and applied sciences|life sciences|biology
    próitéin spíce víreasach Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    spícephróitéin Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    S-próitéin Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    virales Spike-Protein | Spike-Protein | S-Protein
    de
    viral spike protein | spike protein | spike glycoprotein | S-protein
    en
    Definition multifunctional molecular machine that mediates coronavirus entry into host cells Reference "COM-Terminology Coordination, based on: Fang Li. 'Structure, Function, and Evolution of Coronavirus Spike Proteins' (18.3.2020). Annual Review of Virology Vol. 3:237-261 (Volume publication date September 2016) First published online as a Review in Advance on August 25, 2016"
    Comment It first binds to a receptor on the host cell surface through its S1 subunit and then fuses viral and host membranes through its S2 subunit. Two domains in S1 from different coronaviruses recognize a variety of host receptors, leading to viral attachment. The spike protein exists in two structurally distinct conformations, prefusion and postfusion. The transition from prefusion to postfusion conformation of the spike protein must be triggered, leading to membrane fusion
    protéine spike | protéine S
    fr
    Definition protéine virale ancrée dans l'enveloppe virale d'un virus jouant un rôle-clé dans l’entrée dudit virus dans sa cellule-cible Reference "COM-FR, d'après:Serveur TEL - Thèses en ligne, Thèse de doctorat en Virologie, A. Bonnin, Médecine humaine et pathologie, Université du Droit et de la Santé - Lille II (2018), Caractérisation de la protéine S du coronavirus humain 229E (30.4.2020)"
    Comment "Trois protéines virales sont ancrées dans l'enveloppe virale du coronavirus humain 229E: la protéine spike (S), la protéine de membrane (M) et la protéine d’enveloppe (E).La protéine spike (S) est constituée de deux domaines:- le domaine S1, responsable de la liaison du virus à son récepteur;- le domaine S2, responsable de la fusion de l’enveloppe virale avec une membrane cellulaire.Dans le cas du coronavirus humain, la protéine S joue un rôle important dans l'entrée virale."
  2. SCIENCE|natural and applied sciences|life sciences|biology
    spícephróitéin réamhleá Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    pre-fusion spike protein | pre-fusion S protein | prefusion spike protein | prefusion S protein
    en
    Definition "spike protein of SARS-CoV-2 in its conformation before fusion of the virus and host cell membranes" Reference "COM-Terminology Coordination, based on: Proteopedia. 'SARS-CoV-2 spike protein fusion transformation' (18.6.2021)"
  3. SOCIAL QUESTIONS|health|medical science|immunology
    antaigin spícephróitéin COVID-19 Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    S-protein COVID-19 antigen
    en
    Definition "spike protein-based antigen of SARS-CoV-2 used in Sanofi's recombinant-based COVID-19 vaccine candidate" Reference "COM-Terminology Coordination, based on:Sanofi. 'Sanofi and GSK to join forces in unprecedented vaccine collaboration to fight COVID-19' (18.9.2020). Press Release 14.4.2020"
    Comment The DNA sequence encoding this antigen has been combined into the DNA of the baculovirus expression platform, the basis of Sanofi’s licensed recombinant influenza product in the US.
    antigène de la protéine S du virus de la COVID-19 | antigène de la protéine S du COVID-19
    fr
  4. SOCIAL QUESTIONS|health|pharmaceutical industry|pharmaceutical product|vaccine
    spícephróitéin réamhleá SARS-CoV-2 chobhsaithe Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    stabilised SARS-CoV-2 pre-fusion S protein | SARS-CoV2 prefusion Spike delta TM
    en
    Definition "pre-fusion spike protein of SARS-CoV-2 as it has been stabilised in order to be used in a vaccine" Reference "COM-Terminology Coordination, based on:- Paul A Goepfert, Bo Fu, Anne-Laure Chabanon, Matthew I Bonaparte, Matthew G Davis, Brandon J Essink, et al. 'Safety and immunogenicity of SARS-CoV-2 recombinant protein vaccine formulations in healthy adults: interim results of a randomised, placebo-controlled, phase 1–2, dose-ranging study' (18.6.2021). Lancet Infect Dis. April 19, 2021- 'Supplementary appendix 2' (18.6.2021). Supplement to: Goepfert PA, Fu B, Chabanon A-L, et al. Safety and immunogenicity of SARS-CoV-2 recombinant protein vaccine formulations in healthy adults: interim results of a randomised, placebo-controlled, phase 1–2, dose-ranging study. Lancet Infect Dis 2021; published online April 19. https://doi.org/10.1016/S1473-3099(21)00147-X"
    CoV2 preS dTM
    mul