SCIENCE|natural and applied sciences|life sciences|biology|microorganism
- víreas RNA aonsnáithe cialldhiúltaí Reference "Faofa ag an gCoiste Téarmaíochta, www.tearma.ie ;Faomhadh an téarma seo mar chuid de Thionscadal Lex"
- ga
- negative-sense single-stranded RNA virus | negative-stranded RNA virus | (-)ssRNA virus | antisense-strand RNA virus | negative-strand RNA virus
- en
- Definition virus that uses negative sense, single-stranded RNA as its genetic material Reference "Wikipedia > Negative-sense single-stranded RNA virus (28.5.2020)"
- Comment "The genome of an RNA virus can be said to be either positive-sense, also known as a ""plus-strand"", or negative-sense, also known as a ""minus-strand"". In most cases, the terms ""sense"" and ""strand"" are used interchangeably, making terms such as ""positive-strand"" equivalent to ""positive-sense"", and ""plus-strand"" equivalent to ""plus-sense"". Whether a viral genome is positive-sense or negative-sense can be used as a basis for classifying viruses.Negative-sense (3′-to-5′) viral RNA is complementary to the viral mRNA, thus a positive-sense RNA must be produced by an RNA-dependent RNA polymerase from it prior to translation. Like DNA, negative-sense RNA has a nucleotide sequence complementary to the mRNA that it encodes; also like DNA, this RNA cannot be translated into protein directly. Instead, it must first be transcribed into a positive-sense RNA that acts as an mRNA. Some viruses (e.g. influenza viruses) have negative-sense genomes and so must carry an RNA polymerase inside the virion."