SCIENCE|natural and applied sciences|life sciences
- 3'-críoch Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
- ga
- 3'-end | tail end | 3'-terminal
- en
- Definition "DNA or RNA strand which has a hydroxyl (OH) on the 3' carbon of its terminal deoxyribose [ IATE:1479358 ] or ribose [ IATE:1479345 ]" Reference "COM-EN, based on:Gary E. Kaiser. I. MICROBIAL GENETICS. C. DNA REPLICATION http://student.ccbcmd.edu/~gkaiser/biotutorials/dna/dnarep.html [16.3.2012]"
- Comment "The chemical convention of naming carbon atoms in the nucleotide sugar-ring numerically gives rise to a 5′-end and a 3′-end (usually pronounced ""five prime end"" and ""three prime end""). The relative positions of structures along a strand of nucleic acid, including genes and various protein binding sites, are usually noted as being either upstream (towards the 5′-end) or downstream (towards the 3′-end). This naming convention is important because nucleic acids can only be synthesized in vivo in a 5′-to-3′ direction, because the polymerase used to assemble new strands must attach a new nucleotide to the 3′-hydroxyl (-OH) group via a phosphodiester bond. By convention, single strands of DNA and RNA sequences are written in 5′-to-3′ direction."