Gaois

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3 results

  1. SOCIAL QUESTIONS|health|medical science|toxicology

    #617666

    IATE #1073653
    géineatocsaineacht Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    Genotoxizität | Mutagenität
    de
    Definition Wirkungen von chemischen Stoffen, die Änderungen im genetischen Material (Desoxyribonukleinsäure) von Zellen auslösen Reference "Wikipedia, s. v. „Genotoxizität“, https://de.wikipedia.org/wiki/Genotoxizit%C3%A4t (27.9.2017)"
    genotoxicity
    en
    Definition property of an agent to cause specific adverse effects on the genomes of living cells as well the relative toxicity of that agent Reference COM-EN, based on: MacMillan Dictionary of Toxicology, London, 1988
    Comment It can be expressed as a mutagenic or a carcinogenic event because of specific alteration of the molecular structure of the genome through translocation of proto-oncogenes. It results from a reaction with DNA that can be measured either biochemically or, in short-term tests, with endpoints that reflect DNA damage.
  2. SCIENCE|natural and applied sciences|life sciences · SCIENCE|natural and applied sciences|life sciences|biology · SCIENCE|natural and applied sciences|life sciences|biology|genetics

    #626290

    IATE #1354231
    só-ghineacht Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    Mutagenität | Mutationen auslösende Wirkung | mutationsauslösende Wirkung | Mutagenizität
    de
    Definition Fähigkeit von Mutagenen, in einem Organismus Mutationen zu induzieren bzw. die natürliche Mutationsrate zu erhöhen Reference "Lexikon der Biologie. Spektrum Akademischer Verlag: Heidelberg, 1999, s. v. „Mutagenität“, http://www.spektrum.de/lexikon/biologie/mutagenitaet/44501 (10.10.2017)"
    mutagenic potential | mutagenicity potential | mutagenic potency | mutagenicity
    en
    Definition "ability of a compound to induce mutagenicity" Reference "COM-Terminology Coordination, based on: EMA. 'Question and answer document on the Guideline on assessment and control of DNA reactive (mutagenic) impurities in veterinary medicinal products' (22.2.2023) (EMA/CVMP/SWP/377245/2016). EMA/CVMP/SWP/32272/2022. 27 January 2023"
    Comment "See also: structural alert (related)"