Gaois

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  1. SOCIAL QUESTIONS|health|medical science|immunology

    #677108

    IATE #1073436
    T-chill éifeachtóra Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    T-Inducer-Zellen
    de
    effector T cell
    en
    Definition "T cell with limited life span involved in adaptive immunity that has differentiated further after exposure to an antigen and provides the immune system with ""memory"" against previously encountered pathogens" Reference "COM-Terminology Coordination, based on:- ASTRO. 'T Cell Activation and Effector Functions' (3.5.2024)- PluriSelect. 'Effector T cells' (3.5.2024)- Wikipedia > T cell (3.5.2024)"
    Comment "Antigen-naive T cells expand and differentiate into memory and effector T cells after they encounter their cognate antigen within the context of an MHC molecule on the surface of a professional antigen presenting cell (e.g. a dendritic cell). Appropriate co-stimulation must be present at the time of antigen encounter for this process to occur. Historically, memory T cells were thought to belong to either the effector or central memory subtypes, each with their own distinguishing set of cell surface markers (see below).[19] Subsequently, numerous new populations of memory T cells were discovered including tissue-resident memory T (Trm) cells, stem memory TSCM cells, and virtual memory T cells. The single unifying theme for all memory T cell subtypes is that they are long-lived and can quickly expand to large numbers of effector T cells upon re-exposure to their cognate antigen. By this mechanism they provide the immune system with ""memory"" against previously encountered pathogens. Memory T cells may be either CD4+ or CD8+ and usually express CD45RO."