Gaois

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2 results

  1. SOCIAL QUESTIONS|health|medical science|toxicology
    tástáil micreanúicléis Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    tástáil micreanúicléis eiritricíte i mamaigh Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    Mikrokerntest | Mikronukleustest | Mikronukleus-Test
    de
    Definition Test zum Aufdecken von Chromosomenschäden (Chromosomenbruch bzw. klastogener Effekt) und Schäden des Spindelapparates (aneugener Effekt) an sich teilenden Säugetierzellen, der an den lebenden Zellen (in vivo) oder in vitro an Zelllinien (wie z. B. Mouse Lymphoma L5178Y, CHO, V79, TK6) oder primären Zellen (z. B. humanen Lymphozyten) durchgeführt wird Reference "Wikipedia, s. v. „Mikrokerntest“, https://de.wikipedia.org/wiki/Mikrokerntest (23.10.2017)"
    micronucleus test | mammalian in vivo micronucleus test | mammalian erythrocyte micronucleus test | in vivo mammalian erythrocyte micronucleus test
    en
    Definition test used for the detection of damage induced by the test substance to the chromosomes or the mitotic apparatus of erythroblasts by analysis of erythrocytes as sampled in bone marrow and/or peripheral blood cells of animals, usually rodents Reference "Council Regulation (EC) No 440/2008 laying down test methods pursuant to Regulation (EC) No 1907/2006 of the European Parliament and of the Council on the Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH) CELEX:32008R0440/EN"
    Comment "For more information, see: Introduction to Genetic Toxicology. Micronucleus Test, http://www.qed-experiment.com/genetictoxicology/1micronucleustest.html [7.5.2012]"
    épreuve du micronoyau | test de micronucleus | test du micronoyau sur les érythrocytes de mammifère | test du micronoyau | essai du micronoyau
    fr
    Definition Epreuve in vivo à court terme sur mammifère destinée à déceler les lésions chromosomiques ou celles de l'appareil mitotique induites par des substances chimiques Reference Directive 84/449/CEE de la Commission
  2. SOCIAL QUESTIONS|health|medical science|toxicology
    tástáil micreanúicléis in vitro i gcealla mamach Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    in vitro mammalian cell micronucleus test | MNvit assay | in vitro mouse micronucleus test
    en
    Definition "genotoxicity test for the detection of micronuclei [ IATE:1033008 ] (MN) in the cytoplasm [ IATE:1077370 ] of interphase [ IATE:1530134 ] cells" Reference "OECD. Environment Directorate. Chemical Safety and Biosafety. Testing of Chemicals. In Vitro Mammalian Cell Micronucleus Test (MNvit) http://www.oecd.org/LongAbstract/0,3425,en_2649_34377_39780113_1_1_1_1,00.html [13.4.2012]"
    Comment "Micronuclei [ IATE:1033008 ] may originate from acentric chromosome [ IATE:1507541 ] fragments (i.e. lacking a centromere [ IATE:1620877 ]), or whole chromosomes that are unable to migrate to the poles during the anaphase [ IATE:1502711 ] stage of cell division [ IATE:1544625 ]. The assay detects the activity of clastogenic [ IATE:1684795 ] and aneugenic chemicals [ IATE:1588368 ] (substances and mixtures) (1) (2) in cells that have undergone cell division during or after exposure to the test substance."