Gaois

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  1. SCIENCE|natural and applied sciences|life sciences|biology|microorganism
    víreas RNA aonsnáithe cialldheimhní Reference "Faofa ag an gCoiste Téarmaíochta, www.tearma.ie ;Faomhadh an téarma seo mar chuid de Thionscadal Lex"
    ga
    positive-strand RNA virus | positive-sense single-stranded RNA virus | (+)ssRNA
    en
    Definition virus whose genome consists of a single-strand of RNA with polarity similar to mRNA and thus can be immediately translated by the host cell Reference "COM-Terminology Coordination, based on:Lumen. 'Positive-Strand RNA Viruses in Animals' (17.8.2020)"
    Comment Single stranded RNA viruses can be classified according to the sense or polarity of their RNA into negative-sense and positive-sense, or ambisense RNA viruses. Positive-sense viral RNA is similar to mRNA and thus can be immediately translated by the host cell. Negative-sense viral RNA is complementary to mRNA and thus must be converted to positive-sense RNA by an RNA polymerase before translation. As such, purified RNA of a positive-sense virus can directly cause infection though it may be less infectious than the whole virus particle. Purified RNA of a negative-sense virus is not infectious by itself as it needs to be transcribed into positive-sense RNA; each virion can be transcribed to several positive-sense RNAs. Ambisense RNA viruses resemble negative-sense RNA viruses, except they also translate genes from the positive strand.