Gaois

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6 results

  1. SOCIAL QUESTIONS|health|pharmaceutical industry

    #643009

    IATE #3510351
    neart Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    Wirksamkeit
    de
    potency | potent
    en
    Definition expression of the activity of a drug, in terms of the concentration or amount needed to produce a defined effect Reference "Neubig, R., Speeding, M., Kenakin T., et al., 'International Union of Pharmacology Committee on Receptor Nomenclature and Drug Classification. XXXVIII. Update on Terms and Symbols in Quantitative Pharmacology (8.2.2024)', IUPHAR database (IUPHAR-DB), 2003."
    Comment "Drug potency depends on both receptor (affinity, efficacy) and tissue (receptor numbers, drug accessibility) parameters. The term is sometimes, incorrectly, used to refer to the maximum effect attainable.It is usually expressed in milligrams, in I.U. (International Units), etc.Not to be confused with:- strength [ IATE:3518706 ]"
    activité | teneur | puissance
    fr
    Definition relation entre l'effet d'un médicament, mesuré par sa puissance, et sa concentration au niveau du site d'action Reference "COM-FR, d'après le dictionnaire médical de l'Académie de Médecine > activité (18.3.2021)"
  2. SOCIAL QUESTIONS|health|medical science

    #626295

    IATE #1354328
    carcanaigineacht Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    Karzinogenität | Karzinogenizität | Kanzerogenität | karzinogene Wirkung | kanzerogene Wirkung | krebserzeugende Wirkung | krebserregende Wirkung
    de
    Definition Eigenschaft eines Stoffes, Krebs zu erzeugen Reference "DocCheckFlexikon, s. v. „Karzinogenität“, http://flexikon.doccheck.com/de/Karzinogenit%C3%A4t (10.10.2017)"
    carcinogenic potential | carcinogenic potency | carcinogenicity
    en
    Definition ability of a chemical or physical agent to induce cancer Reference "COM-Terminology Coordination, based on: John E. Doe, Alan R. Boobis, Vicki Dellarco, Penelope A. Fenner-Crisp, Angelo Moretto, Timothy P. Pastoor, Rita S. Schoeny, Jennifer G. Seed, Douglas C. Wolf. 'Chemical carcinogenicity revisited 2: Current knowledge of carcinogenesis shows that categorization as a carcinogen or non-carcinogen is not scientifically credible' (13.6.2023). Regulatory Toxicology and Pharmacology, Volume 103, 2019, Pages 124-129, ISSN 0273-2300,"
  3. SCIENCE|natural and applied sciences|life sciences · SCIENCE|natural and applied sciences|life sciences|biology · SCIENCE|natural and applied sciences|life sciences|biology|genetics

    #626290

    IATE #1354231
    só-ghineacht Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    Mutagenität | Mutationen auslösende Wirkung | mutationsauslösende Wirkung | Mutagenizität
    de
    Definition Fähigkeit von Mutagenen, in einem Organismus Mutationen zu induzieren bzw. die natürliche Mutationsrate zu erhöhen Reference "Lexikon der Biologie. Spektrum Akademischer Verlag: Heidelberg, 1999, s. v. „Mutagenität“, http://www.spektrum.de/lexikon/biologie/mutagenitaet/44501 (10.10.2017)"
    mutagenic potential | mutagenicity potential | mutagenic potency | mutagenicity
    en
    Definition "ability of a compound to induce mutagenicity" Reference "COM-Terminology Coordination, based on: EMA. 'Question and answer document on the Guideline on assessment and control of DNA reactive (mutagenic) impurities in veterinary medicinal products' (22.2.2023) (EMA/CVMP/SWP/377245/2016). EMA/CVMP/SWP/32272/2022. 27 January 2023"
    Comment "See also: structural alert (related)"
  4. SOCIAL QUESTIONS|health|pharmaceutical industry

    #664804

    IATE #3592868
    bithmheasúnacht neartúlachta Reference "Rialachán Tarmligthe (AE) 2021/805 lena leasaítear Iarscríbhinn II a ghabhann le Rialachán (AE) 2019/6 ó Pharlaimint na hEorpa agus ón gComhairle, CELEX:32021R0805/GA ;Faomhadh an téarma seo mar chuid de Thionscadal Lex"
    ga
    Potenz-Bioassay
    de
    potency bioassay
    en
    Definition "test that measures the biological activity (potency) of a biological pharmaceutical substance" Reference "COM-Terminology Coordination, based on: 'Optimising Bioassays for Biologics. 6th Annual' (17.2.2021). PEGSBoston. Cambridge Innovation Institute (CHI)"
    bioessai d'activité
    fr
    Definition "essai mesurant l’activité d’un médicament biologique" Reference "COM-FR, d'après:- COM-Terminology Coordination- Université de Lausanne, Faculté de biologie et de médecine, échos du vivant n° 3, septembre-novembre 2015, «La dure vie de nos amis les microbes» (18.3.2021)"
  5. SOCIAL QUESTIONS|health|pharmaceutical industry

    #624361

    IATE #1259254
    tástáil neartúlachta Reference "Rialachán Tarmligthe (AE) 2021/805 lena leasaítear Iarscríbhinn II a ghabhann le Rialachán (AE) 2019/6 ó Pharlaimint na hEorpa agus ón gComhairle, CELEX:32021R0805/GA"
    ga
    Potenzprüfung
    de
    potency test | potency testing
    en
    Definition "quantitative test that measures the concentration of the active substance (or of the active pharmaceutical ingredient) in a sample" Reference "COM-Terminology Coordination, based on: Potency Testing Benefits and Requirements (17.2.2021). ARL Biopharma"
    essai d'activité
    fr
    Definition essai quantitatif mesurant la concentration d'une substance active dans un échantillon Reference COM-FR, d'après COM-Terminology Coordination