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  1. SCIENCE|natural and applied sciences|life sciences

    #648469

    IATE #3541918
    5'-críoch Tagairt Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    5'-end
    en
    Sainmhíniú "the end of the DNA or RNA strand that has the fifth carbon in the sugar-ring of the deoxyribose [ IATE:1479358 ] or ribose [ IATE:1479345 ] at its terminus" Tagairt "Wikpedia. Directionality (molecular biology) http://en.wikipedia.org/wiki/Directionality_%28molecular_biology%29 [16.3.2012]"
    Nóta "The chemical convention of naming carbon atoms in the nucleotide sugar-ring numerically gives rise to a 5′-end and a 3′-end (usually pronounced ""five prime end"" and ""three prime end""). The relative positions of structures along a strand of nucleic acid, including genes and various protein binding sites, are usually noted as being either upstream (towards the 5′-end) or downstream (towards the 3′-end). This naming convention is important because nucleic acids can only be synthesized in vivo in a 5′-to-3′ direction, because the polymerase used to assemble new strands must attach a new nucleotide to the 3′-hydroxyl (-OH) group via a phosphodiester bond. By convention, single strands of DNA and RNA sequences are written in 5′-to-3′ direction."