Gaois

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4 results

  1. SOCIAL QUESTIONS|health|medical science

    #628252

    IATE #1431340
    T-chill sochta Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    T-limficít sochta Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    T-Supressor Lymphozyt | Suppressorzellen | T-Suppressorzelle | Suppressor-T-Lymphozyten
    de
    regulatory T cell | Treg | suppressor T lymphocyte | T suppressor lymphocyte | suppressor T cell | T-suppressor cell | Tregs
    en
    Definition "T cell whose major role is to shut down T cell-mediated immunity [ IATE:1528623 ] toward the end of an immune reaction and to suppress auto-reactive T cells that escaped the process of negative selection in the thymus" Reference "Wikipedia > T cell (23.3.2021)"
    Comment "They are crucial for the maintenance of immunological tolerance.Two major classes of CD4+ Treg cells have been described — Foxp3+ Treg cells and Foxp3- Treg cells.Regulatory T cells can develop either during normal development in the thymus, and are then known as thymic Treg cells, or can be induced peripherally and are called peripherally derived Tregs. These two subsets were previously called ""naturally occurring"", and ""adaptive"" or ""induced"", respectively."
    lymphocyte T supresseur | lymphocytes T-suppresseurs | T suppressif | lymphocyte T cytotoxique | lymphocyte T suppresseur
    fr
  2. SCIENCE|natural and applied sciences|life sciences|biology · SOCIAL QUESTIONS|health|medical science|immunology

    #620209

    IATE #1128334
    T-chill chuimhne Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    memory T lymphocyte | memory T cell
    en
    Definition "antigen-specific T cell that persists long-term after an infection has resolved and which expands quickly to large numbers of effector T cells upon re-exposure to their cognate antigen, thus providing a rapid response to past infection" Reference "COM-Terminology Coordination, based on: Bryan Tungland. 'Chapter 4 - Role of Gut Microbiota in Immune Homeostasis' (20.10.2021). In: Human Microbiota in Health and Disease From Pathogenesis to Therapy 2018, Pages 135-154"
    Comment Memory T cells are either CD4+ or the virus-specific CD8+ depending on the type of antigen encountered (MacLeod et al., 2010). The memory T cells include subtypes, central memory T cells (Tcm cells), effector memory T cells (Tem cells and Temra cells) (Willinger et al., 2005), as subtypes. They also typically express CD45RO cell surface protein (Valentine et al., 2013, Akbar et al., 1988).
    lymphocyte T mémoire
    fr
    Definition lymphocyte T chargé de conserver le souvenir des protéines déjà rencontrées Reference Pour la Science,novembre 1993
  3. SOCIAL QUESTIONS|health|medical science|immunology

    #677108

    IATE #1073436
    T-chill éifeachtóra Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    T-Inducer-Zellen
    de
    effector T cell
    en
    Definition "T cell with limited life span involved in adaptive immunity that has differentiated further after exposure to an antigen and provides the immune system with ""memory"" against previously encountered pathogens" Reference "COM-Terminology Coordination, based on:- ASTRO. 'T Cell Activation and Effector Functions' (3.5.2024)- PluriSelect. 'Effector T cells' (3.5.2024)- Wikipedia > T cell (3.5.2024)"
    Comment "Antigen-naive T cells expand and differentiate into memory and effector T cells after they encounter their cognate antigen within the context of an MHC molecule on the surface of a professional antigen presenting cell (e.g. a dendritic cell). Appropriate co-stimulation must be present at the time of antigen encounter for this process to occur. Historically, memory T cells were thought to belong to either the effector or central memory subtypes, each with their own distinguishing set of cell surface markers (see below).[19] Subsequently, numerous new populations of memory T cells were discovered including tissue-resident memory T (Trm) cells, stem memory TSCM cells, and virtual memory T cells. The single unifying theme for all memory T cell subtypes is that they are long-lived and can quickly expand to large numbers of effector T cells upon re-exposure to their cognate antigen. By this mechanism they provide the immune system with ""memory"" against previously encountered pathogens. Memory T cells may be either CD4+ or CD8+ and usually express CD45RO."
  4. PRODUCTION, TECHNOLOGY AND RESEARCH|technology and technical regulations|biotechnology · SOCIAL QUESTIONS|health|pharmaceutical industry · SOCIAL QUESTIONS|health|illness|cancer

    #684942

    IATE #3578242
    T-chill gabhdóra chiméaraigh aintaiginí Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    chimeric antigen receptor T cell | CAR T cell | CAR-T cell
    en
    Definition "T-lymphocyte which is genetically modified by adding a gene expressing a special receptor (called a chimeric antigen receptor) through which it is targeted against surface components of tumour cells in order to kill those cells" Reference "COM-Terminology Coordination, based on:Kieran Breen. 'Chimeric antigen receptor (CAR) T cell therapies' (30.4.2024). European Medicines Agency (EMA)"