Gaois

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2 results

  1. SCIENCE|natural and applied sciences|life sciences|biology
    caidéal eisilte Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    Efflux-Pumpe
    de
    efflux pump
    en
    Definition any transport protein, found in both Gram-positive and -negative bacteria as well as in eukaryotic organisms, and involved in the extrusion of toxic substrates (including virtually all classes of clinically relevant antibiotics) from within cells into the external environment Reference "COM-EN, based on: M.A. Webber, L.J.V. Piddock. The importance of efflux pumps in bacterial antibiotic resistance. 2003. Journal of Antimicrobial Chemotherapy, 51(1), https://doi.org/10.1093/jac/dkg050 [22.5.2018]"
    Comment "Pumps may be specific for one substrate or may transport a range of structurally dissimilar compounds (including antibiotics of multiple classes); such pumps can be associated with multiple drug resistance (MDR).Reference: M.A. Webber, L.J.V. Piddock. The importance of efflux pumps in bacterial antibiotic resistance. 2003. Journal of Antimicrobial Chemotherapy, 51(1), https://doi.org/10.1093/jac/dkg050 [22.5.2018]"
    pompe à efflux | efflux actif
    fr
    Definition pompe membranaire par laquelle les antibiotiques sont rejetés à l'extérieur des bactéries Reference "COM-FR, d'après:- Site de michel.deleuil.free.fr > La résistance aux antibiotiques > Les phénomènes de résistance > «Les processus de résistance», (24.3.2013), http://michel.deleuil.free.fr/phenomene_de_resistance_2.html [2.7.2018]- Dictionnaire de l'académie nationale de pharmacie en ligne > efflux, http://dictionnaire.acadpharm.org/w/Efflux [24.7.2018]"
    Comment "La pompe à efflux constitue un des mécanismes de résistance aux antibiotiques. 5Source: Site de michel.deleuil.free.fr > La résistance aux antibiotiques > Les phénomènes de résistance > «Les processus de résistance», (24.3.2013), http://michel.deleuil.free.fr/phenomene_de_resistance_2.html [2.7.2018])"
  2. SCIENCE|natural and applied sciences|life sciences|biology
    caidéal eisilte ildrugaí Reference "Faofa ag an gCoiste Téarmaíochta, www.tearma.ie Faomhadh an téarma seo mar chuid de Thionscadal Lex"
    ga
    multidrug efflux pump
    en
    Definition transport protein, found in both Gram-positive and -negative bacteria as well as in eukaryotic organisms, and involved in the extrusion of antimicrobials from within cells into the external environment Reference "COM-Terminology Coordination, based on: - M.A. Webber, L.J.V. Piddock. 'The importance of efflux pumps in bacterial antibiotic resistance' (18.3.2022). 2003. Journal of Antimicrobial Chemotherapy, 51(1)- Blanco P, Hernando-Amado S, Reales-Calderon JA, et al. 'Bacterial Multidrug Efflux Pumps: Much More Than Antibiotic Resistance Determinants' (18.3.2022). Microorganisms. 2016;4(1):14. Published 2016 Feb 16."
    Comment Pumps may be specific for one substrate or may transport a range of structurally dissimilar compounds (including antibiotics of multiple classes); such pumps can be associated with multiple drug resistance (MDR).