Gaois

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  1. SCIENCE|natural and applied sciences|life sciences|biology

    #667082

    IATE #3627422
    caidéal eisilte ildrugaí Reference "Faofa ag an gCoiste Téarmaíochta, www.tearma.ie Faomhadh an téarma seo mar chuid de Thionscadal Lex"
    ga
    multidrug efflux pump
    en
    Definition transport protein, found in both Gram-positive and -negative bacteria as well as in eukaryotic organisms, and involved in the extrusion of antimicrobials from within cells into the external environment Reference "COM-Terminology Coordination, based on: - M.A. Webber, L.J.V. Piddock. 'The importance of efflux pumps in bacterial antibiotic resistance' (18.3.2022). 2003. Journal of Antimicrobial Chemotherapy, 51(1)- Blanco P, Hernando-Amado S, Reales-Calderon JA, et al. 'Bacterial Multidrug Efflux Pumps: Much More Than Antibiotic Resistance Determinants' (18.3.2022). Microorganisms. 2016;4(1):14. Published 2016 Feb 16."
    Comment Pumps may be specific for one substrate or may transport a range of structurally dissimilar compounds (including antibiotics of multiple classes); such pumps can be associated with multiple drug resistance (MDR).