SOCIAL QUESTIONS|health|illness · SOCIAL QUESTIONS|health|medical science
- galar na gcnámh briosc Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
- ga
- oistéigineas neamhfhoirfe de chineál I Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
- ga
- Adair-Dighton-Syndrom | Lobstein-Syndrom | Blegvad-Haxthausen-Syndrom | Osteopsathyrosis
- de
- Definition Erbleiden mit generalisierter Hypostose und dadurch abnormer Knochenbrüchigkeit infolge Hemmung der Osteoblastenfunktion Reference Reallex Med
- Comment Erkrankung, die aufgrund eines autosomal-rezessiv erblichen Insulinrezeptordefekts mit Hyperinsulinämie u. zusätzlich phänotyp. Charakteristika (intrauterine Wachstumsverzögerung u. Minderwuchs, Hypertrichose, Pseudoacanthosis nigricans, sog. Elfengesicht, Ovarialzysten etc.) einhergeht.;1)O.i.t. Typ Lobstein s. tarda; Osteopsathyrosis idiopathica, Fragilitas ossium hereditaria s. tarda, Ekman-Lobstein Syndrom: autosomal-dominant erbliche gutartige Form der Osteogenesis imperfecta mit mangelhafter periostaler Knochenbildung
- osteogenesis imperfecta | osteogenesis imperfecta tarda | osteogenesis imperfecta type I | Blegvad-Haxthausen syndrome | Lobstein’s disease | Lobstein disease | Adair Dighton syndrome | brittle bone syndrome | brittle bone disease | glass bone disease
- en
- Definition Osteogenesis imperfecta (OI) is the most common disease causing fractures in childhood. It also causes fractures in adults. OI is a genetic disorder usually resulting from abnormalities of the genes that control the production of a protein known as collagen; this is the main protein in bone and essential for its strength. The fragility of bone in OI is due to the collagen problems; it has nothing to do with the calcium part of bone which is what shows on x-rays.[...] OI in an individual is present from the time of conception. In some cases, mostly the milder ones, the disorder passes from one generation to another. In some ‘mild’ cases and most severe cases, it arises without any family history. In most, but not all, of these the cause is a ‘new genetic mutation’. Reference "Tayside University Hospitals, National Health Service Trust Hospital (UK) , http://www.dundee.ac.uk/medther/tayendoweb/images/brittle_bone_disease.htm#What%20is%20osteogenesis , (04.04.2008)"
- ostéogénèse imparfaite | ostéogenèse imparfaite tardive | syndrome de Blegvad-Haxthausen | maladie de Lobstein | maladie des os de verre | ostéopsathyrose | syndrome d'Adair-Dighton | dysplasie périostale
- fr
- Definition trouble de la formation des os qui sont fragiles avec fractures spontanées liées à des anomalies du tissu conjonctif par défaut de constitution du collagène. Reference La Banque des mots, N°66, 2003