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  1. SOCIAL QUESTIONS|health|pharmaceutical industry

    #653182

    IATE #3562703
    dáileadh fíocháin Tagairt Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    tissue distribution
    en
    Sainmhíniú reversible movement of a test chemical from one location in the body to another Tagairt "OECD. Test No. 417: Toxicokinetics.OECD Guidelines for the Testing of Chemicals, Section 1. ISSN: 2074-5788 (online). ISBN: 9789264070882 (PDF), http://www.oecd-ilibrary.org/environment/test-no-417-toxicokinetics_9789264070882-en [24.10.2014]"
    Nóta Tissue distribution can be studied by organ dissection, homogenisation, combustion and liquid scintillation counting or by qualitative and/or quantitative whole body autoradiography. The former is useful to obtain concentration and percent of recovery from tissues and remaining carcass of the same animals, but may lack resolution for all tissues and may have less than ideal overall recovery (<90%).