SCIENCE|natural and applied sciences|life sciences|biology
- géin V Tagairt "Faofa ag an gCoiste Téarmaíochta, www.tearma.ie Faomhadh an téarma seo mar chuid de Thionscadal Lex"
- ga
- deighleog de ghéin V Tagairt "Faofa ag an gCoiste Téarmaíochta, www.tearma.ie Faomhadh an téarma seo mar chuid de Thionscadal Lex"
- ga
- deighleog de ghéin athraitheach Tagairt "Faofa ag an gCoiste Téarmaíochta, www.tearma.ie Faomhadh an téarma seo mar chuid de Thionscadal Lex"
- ga
- V-gene | V gene segment | variable gene segment
- en
- Sainmhíniú "in human immunoglobulins, gene segment that encodes a variable region" Tagairt "COM-Terminology Coordination, based on:SR BAUER. 'B-CELL DIFFERENTIATION AND RISKS FOR NEOPLASTIC TRANSFORMATION' (1.10.2020)"
- Nóta Human antibody molecules (including B cell receptors) are composed of heavy and light chains, each of which contains both constant (C) and variable (V) regions, genetically encoded on three loci: - The immunoglobulin heavy locus (IGH@) on chromosome 14, containing the gene segments for the immunoglobulin heavy chain.- The immunoglobulin kappa (κ) locus (IGK@) on chromosome 2, containing the gene segments for part of the immunoglobulin light chain. - The immunoglobulin lambda (λ) locus (IGL@) on chromosome 22, containing the gene segments for the remainder of the immunoglobulin light chain. Each heavy chain or light chain gene contains multiple copies of three different types of gene segments for the variable regions of the antibody proteins. For example, the human immunoglobulin heavy chain region contains 2 Constant (Cμ and Cδ) gene segments and 44 Variable (V) gene segments, plus 27 Diversity (D) gene segments and 6 Joining (J) gene segments. The light chain genes possess either a single (Cκ) or four (Cλ) Constant gene segments with numerous V and J gene segments but do not have D gene segments. DNA rearrangement causes one copy of each type of gene segment to go in any given lymphocyte, generating an enormous antibody repertoire; roughly 3×1011 combinations are possible, although some are removed due to self reactivity.
- segment de gène V | gène de variabilité | gène V
- fr
- Sainmhíniú 1) partie de la séquence d'un gène V 2) gène commandant la production de protéines servant de site de fixation aux superantigènes bactériens Tagairt Dict.de génétique,CILF,1991