SOCIAL QUESTIONS|health|pharmaceutical industry
- analóg núicléisíde Tagairt Faomhadh an téarma seo mar chuid de Thionscadal Lex
- ga
- Nukleosidanalog | Nukleosid-Analogon | Nukleosidanalogon
- de
- Sainmhíniú Substanzen, die natürlichen Nukleosiden ähneln, wie z. B. die nukleosidischen Reverse-Transkriptase-Inhibitoren (NRTI), und als Arzneistoffe vor allem in der antiviralen Therapie angewendet werden, z.B. gegen HIV, HBV und HBC Tagairt "DocCheckFlexikon, s. v. „Nukleosidanalogon“, http://flexikon.doccheck.com/de/Nukleosidanalogon (24.10.2017)"
- nucleoside analog | nucleoside analogue
- en
- Sainmhíniú synthetic molecule that resembles a naturally occuring nucleoside, but that lacks a bond site needed to link it to an adjacent nucleotide Tagairt "'nucleoside analog' (19.10.2021). Hedgehog Signaling Glossary"
- Nóta Nucleoside analogues (NA) constitute an important class of antimetabolites used in the treatment of hematological malignancies and, more recently, in solid tumors. These therapeutic compounds mimic physiological nucleosides in terms of uptake and metabolism and are incorporated into newly synthesized DNA resulting in synthesis inhibition and chain termination. Some of these drugs also inhibit key enzymes involved in the generation of the purine and pyrimidine nucleotides and RNA synthesis, and directly activate the caspase cascade. All of these effects may lead to cell death.
- analogue nucléosidique | analogue de nucléoside
- fr
- Sainmhíniú composé synthétique similaire à l'un des nucléotides présents dans l'ADN ou l'ARN d'un virus ou d'un rétrovirus Tagairt Act Up-Paris,Gloss.sida,janvier 1998