SOCIAL QUESTIONS|health|medical science
- cill strómach Tagairt Faomhadh an téarma seo mar chuid de Thionscadal Lex
- ga
- stromal cell | mesenchymal stromal cell | MSC
- en
- Sainmhíniú connective tissue cell present in all bodily organs with notable secretory, immunomodulatory and homing properties Tagairt "COM-Terminology Coordination, based on: - Marc BAJENOFF. 'Stromal cells' (26.11.2024). Immunobiology of stromal cells. Centre d’Immunologie de Marseille-Luminy.- S. Viswanathan, Y. Shi, J. Galipeau, M. Krampera, K. Leblanc, I. Martin, J. Nolta, D.G. Phinney, L. Sensebe. 'Mesenchymal stem versus stromal cells: International Society for Cell & Gene Therapy (ISCT®) Mesenchymal Stromal Cell committee position statement on nomenclature' (26.11.2024). Cytotherapy Volume 21, Issue 10, October 2019, Pages 1019-1024"
- Nóta The International Society for Cell & Gene Therapy (ISCT®) Mesenchymal Stromal Cell (ISCT MSC) committee issued a position paper in 2005 clarifying that the term mesenchymal stem cell is not equivalent or interchangeable with mesenchymal stromal cell (MSC). The former refers to a stem cell population with demonstrable progenitor cell functionality of self-renewal and differentiation, whereas the latter refers to a bulk population with notable secretory, immunomodulatory and homing properties. The ISCT's MSC committee further issued a minimal criteria to define multipotent MSCs as being plastic adherent, expressing CD73, CD90 and CD105, lacking the expression of hematopoietic and endothelial markers CD11b, CD14, CD19, CD34, CD45, CD79a and HLA-DR and capable of in vitro differentiation into adipocyte, chondrocyte and osteoblast lineages