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22 toradh

  1. SOCIAL QUESTIONS|health|pharmaceutical industry

    #648742

    IATE #3543826
    coscaire ocsaíodáise xaintín Tagairt Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    xanthine oxidase inhibitor | inhibitors
    en
    Sainmhíniú "any substance that inhibits the activity of xanthine oxidase [ IATE:1898644 ]" Tagairt "Wikipedia. Xanthine oxidase inhibitor http://en.wikipedia.org/wiki/Xanthine_oxidase_inhibitor [22.5.2012]"
    Nóta In humans, inhibition of xanthine oxidase reduces the production of uric acid, and several medications that inhibit xanthine oxidase are indicated for treatment of hyperuricemia and related medical conditions including gout.Xanthine oxidase inhibitors are of two kinds: purine analogues and others. Purine analogues include allopurinol, oxypurinol, and tisopurine. Others include febuxostat and inositols (phytic acid and myo-inositol).
  2. SOCIAL QUESTIONS|health|pharmaceutical industry · SCIENCE|natural and applied sciences|life sciences

    #617994

    IATE #1079226
    coscaire topaisiméaráise Tagairt Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    Topoisomerasehemmer | Topoisomerase-Hemmer | Topoisomerase-Inhibitor
    de
    Sainmhíniú Hemmstoff der Topoisomerase; Zytostatikum Tagairt "Roche Lexikon Medizin, Urban & Fischer: 2003, 5. Aufl., s. v. „C. thoracis“, www.roche.de&content=/lexikon/suche.html" rel="noopener noreferrer" target="_blank">https://www.roche.de/lexikon/index.htm?loc=www.roche.de&content=/lexikon/suche.html> (26.10.2017)"
    Nóta Wirkstoff: a) Topoisomerase-I-Inhibitoren: Topotecan u. Irinotecan; b) Topoisomerase-II-Inhibitoren: Etoposid u. Teniposid (Podophyllotoxin-Derivate); Wirkung: verursachen Brüche der DNS-Stränge, dadurch Hemmung der Replikation. Nebenwirkungen: u.a. Myelosuppression, Nausea, Erbrechen, Alopezie u. v.a. unter Irinotecan schwere Durchfälle.
    topoisomerase inhibitor | inhibitors
    en
    Sainmhíniú "group of agents designed to interfere with the action of topoisomerase enzymes (topoisomerase I and II), which are enzymes that control the changes in DNA structure by catalyzing the breaking and rejoining of the phosphodiester backbone of DNA strands during the normal cell cycle [ IATE:1544625 ]" Tagairt "Wikipedia http://en.wikipedia.org/wiki/Topoisomerase_inhibitor [21.9.2010]"
    Nóta In recent years, topoisomerases have become popular targets for cancer chemotherapy treatments. They can also function as antibacterial agents.
    inhibiteur de la topoisomérase
    fr
    Sainmhíniú il inhibe la capacité de la topoisomérase à relier les deux bouts coupés des brins de l'ADN, tue la cellule, car les brins libérés perturbent mortellement son fonctionnement Tagairt Pour la Science,Novembre 1996