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3 thoradh

  1. SCIENCE|natural and applied sciences|life sciences|pharmacology

    #624788

    IATE #1323258
    freasaitheach gabhdóra Tagairt Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    antagonist | receptor antagonist
    en
    Sainmhíniú "drug that reduces the action of another drug, generally an agonist " Tagairt "RICHARD R. NEUBIG, MICHAEL SPEDDING, TERRY KENAKIN, AND ARTHUR CHRISTOPOULOS. 'International Union of Pharmacology Committee on Receptor Nomenclature and Drug Classification. XXXVIII. Update on Terms and Symbols in Quantitative Pharmacology' (4.2.2022). PHARMACOLOGICAL REVIEWS. Vol. 55, No. 4. The American Society for Pharmacology and Experimental Therapeutics"
    Nóta Can be competitive or non-competitive, each of which can be reversible or irreversible. A competitive antagonist binds to the same site as the agonist but does not activate it, thus blocks the agonist’s action. A non-competitive antagonist binds to an allosteric (non-agonist) site on the receptor to prevent activation of the receptor. A reversible antagonist binds non-covalently to the receptor, therefore can be “washed out”. An irreversible antagonist binds covalently to the receptor and cannot be displaced by either competing ligands or washing.
  2. SOCIAL QUESTIONS|health|pharmaceutical industry

    #617689

    IATE #1073759
    aidréinealaíoch Tagairt Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    Antiadrenergikum | Adrenolytikum
    de
    Sainmhíniú Wegen der hemmenden Wirkung auf die adrenergen Sympathicus-Nerven verwendete Bezeichnung für Alpha-und Beta-Rezeptoren-Blocker. Tagairt Römpp
    adrenergic blocking agent | adrenergic blocking activity | adrenergic receptor antagonist | adrenolytic
    en
    Sainmhíniú "drug inhibiting the action of the adrenergic receptors [ IATE:1073476 ]" Tagairt "COM-EN, based on:ROBERT K. GRIFFITH. Chapter One: Adrenergics and Adrenergic-Blocking Agents. Burger’s Medicinal Chemistry and Drug DiscoverySixth Edition, Volume 6: Nervous System Agents. Edited by Donald J. AbrahamISBN 0-471-27401-1 ©2003 John Wiley&Sons, Inc. http://media.wiley.com/product_data/excerpt/11/04712740/0471274011.pdf [31.5.2012]"
    Nóta "They can be divided into: alpha blockers [ IATE:1686921 ] and beta blockers [ IATE:1073758 ]Not to be confused with the superordinate concept antiadrenergic which includes include adrenergic blocking agents, both alpha- and beta-blockers, and adrenergic neuron-blocking drugs and catecholamine depleting agents."
    adrénolytique
    fr
    Sainmhíniú Se dit de toute substance capable de diminuer ou de supprimer l'action de l'adrénaline sur les récepteurs adrénergiques alpha ou bêta. Tagairt Touitou,p.44;Flammarion
  3. SOCIAL QUESTIONS|health|pharmaceutical industry

    #639229

    IATE #2224770
    blocálaí gabhdóirí angaitheannaine Tagairt Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    Angiotensin-Rezeptor-Blocker | ARB | Angiotensin II-Hemmer | Angiotensin II-Antagonist
    de
    Sainmhíniú Medikament zur Hemmung der Wirkung des Hormons Angiotensin II Tagairt "eesom, http://www.eesom.com/de/anginapectoris.php (01.06.2007)"
    Nóta wirkt als spezifischer Hemmstoff am Subtyp 1 des Angiotensin-II-Rezeptors und senkt den Gefäßwiderstand im Körper
    angiotensin-receptor blocker | angiotensin II inhibitor | AII inhibitor | ARB | angiotensin receptor antagonist | ARA | angiotensin II type 1 receptor blocker | angiotensin II type 1 receptor antagonist
    en
    Sainmhíniú hypertension drugs that prevent angiotensin II from binding with its receptors on the surface of the cells Tagairt COM/DGT-Terminology Coordination
    Nóta "the hypertension drugs that prevent the conversion of angiotensin I to angiotensin II are called ""angiotensin-converting enzyme inhibitors"" (ACE inhibitors or ACEI) [ IATE:1040702 ]. For more information, see also: Angiotensin II Receptor Blockers http://www.ti.ubc.ca/pages/letter28.htm [31.5.2007]"
    antagoniste des récepteurs de l'angiotensine II | ARA II | ARA-II | ARAII | ARA | bloqueur des récepteurs de l'angiotensine II | antagoniste des récepteurs AT1 de l'angiotensine II | bloqueur des récepteurs AT1 de l'angiotensine II
    fr
    Sainmhíniú médicament pour le traitement de l'hypertension et de l'insuffisance cardiaque congestive qui bloque la fixation de l'angiotensine sur ses récepteurs (AT1 , AT2) Tagairt "Sur la base de: Facultés universitaires Notre-Dame de la Paix, Namur, http://www.fundp.ac.be/recherche/projets/page_view/94273108/ [1.6.2007] et amc.ca, Racine N., White M. Le rôle des bloqueurs des récepteursde AT-II dans l'insuffisance cardiaque congestive, http://www.cma.ca/index.cfm/ci_id/24826/la_id/2.htm [1.6.2007]"
    Nóta "il existe deux sortes de récepteurs de l'angiotensine, les récepteurs AT1 et les récepteurs AT2. La plupart des médicaments bloquent les récepteurs AT1. A ne pas confondre avec les médicaments qui inhibent la production de l'angiotensine II [ IATE:1040702 ]"