SCIENCE|natural and applied sciences|physical sciences|chemistry|analytical chemistry
- ultra-performance liquid chromatography | UPLC | ultra-high performance liquid chromatography | UHPLC
- en
- Definition "high-pressure liquid chromatography (HPLC) technique that employs columns packed with sub-2-micron particles, which allows for higher resolution and faster separations compared to traditional HPLC methods" Reference "Creative Proteomics. 'Ultra-Performance Liquid Chromatography (UPLC): Principles, Advantages, and Applications' (15.1.2025)"
- Comment UPLC systems typically operate at higher pressures and utilize smaller particle sizes, resulting in improved efficiency, sensitivity, and speed of analysis. This technology is widely used in various fields such as pharmaceuticals, food and beverage analysis, environmental testing, and biochemistry for the separation, identification, and quantification of compounds in complex mixtures.