SOCIAL QUESTIONS|health|medical science
- measúnacht útaratrófach Tagairt Faomhadh an téarma seo mar chuid de Thionscadal Lex
- ga
- uterotrophic assay | uterotrophic bioassay
- en
- Sainmhíniú short-term screening test based on the increase in uterine weight or uterotrophic (positive influence on the growth of uterine tissues) response which evaluates the ability of a chemical to elicit biological activities consistent with agonists or antagonists of natural oestrogens Tagairt "COM-Terminology Coordination, based on:OCDE. OECD Guidelines for the Testing of Chemicals, Section 4. Test No. 440: Uterotrophic Bioassay in Rodents: A short-term screening test for oestrogenic properties, http://www.oecd-ilibrary.org/environment/test-no-440-uterotrophic-bioassay-in-rodents_9789264067417-en [11.8.2014]"
- Nóta However, the use of this test for antagonist detection is much less common than for agonists. The uterus responds to oestrogens in two ways. An initial response is an increase in weight due to water imbibition. This response is followed by a weight gain due to tissue growth. The uterus responses in rats and mice qualitatively are comparable.