SOCIAL QUESTIONS|health|illness|cancer
- fibreablast atá bainteach le hailse Tagairt Faomhadh an téarma seo mar chuid de Thionscadal Lex
- ga
- cancer‐associated fibroblast | CAF
- en
- Sainmhíniú "cell that is a central component of the tumour microenvironment in primary and metastatic tumours, profoundly influences the behaviour of cancer cells and is involved in cancer progression through extensive interactions with cancer cells and other normal epithelial cells" Tagairt "COM-Terminology Coordination, based on: - David Kryza, Jennifer Wischhusen, Mathieu Richaud, Maëva Hervieu, Jacqueline Sidi Boumedine, Jean‐Guy Delcros, Sophie Besse, Thomas Baudier, Pierre‐Alexandre Laval, Silvia Breusa, Erwan Boutault, Hugo Clermidy, Nicolas Rama, Benjamin Ducarouge, Mojgan Devouassoux‐Shisheboran, Jean‐Michel Chezal, Anne‐Laure Giraudet, Thomas Walter, Patrick Mehlen, David Sarrut & Benjamin Gibert. 'From netrin-1-targeted SPECT/CT to internal radiotherapy for management of advanced solid tumors' (26.11.2024). EMBO Molecular Medicine (2023) 15: e16732- Yang, D., Liu, J., Qian, H. et al. 'Cancer-associated fibroblasts: from basic science to anticancer therapy' (26.11.2024). Experimental & Molecular Medicine 55, 1322–1332 (2023). "
- Nóta CAFs may be derived from fibroblasts, epithelial cells, endothelial cells, cancer stem cells, adipocytes, pericytes, or stellate cells. These complex origins may underlie their functional diversity, which includes pro-tumorigenic roles in extracellular matrix remodeling, the suppression of anti-tumor immunity, and resistance to cancer therapy.