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2 thoradh

  1. SCIENCE|natural and applied sciences|life sciences|biology
    próitéin CRISPR-bhainteach Tagairt Faomhadh an téarma seo mar chuid de Thionscadal Lex
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    Cas Tagairt Faomhadh an téarma seo mar chuid de Thionscadal Lex
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    núicléáis Cas Tagairt Faomhadh an téarma seo mar chuid de Thionscadal Lex
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    Cas | CRISPR-associated protein | Cas nuclease
    en
    Sainmhíniú "protein (enzyme) found near clustered regularly interspaced short palindromic repeats (CRISPRs) and associate with CRISPR RNAs to bind to, and alter DNA or RNA target sequences" Tagairt "COM-Terminology Coordination, based on: - 'Cas (CRISPR Associated Protein)' (14.1.2021). Glossary. BioNews- Daniel H Haft, Jeremy Selengut, Emmanuel F Mongodin, and Karen E Nelson. 'A Guild of 45 CRISPR-Associated (Cas) Protein Families and Multiple CRISPR/Cas Subtypes Exist in Prokaryotic Genomes' (14.1.2021), PLoS Computational Biology, 2005 Nov; 1(6): e60."
  2. PRODUCTION, TECHNOLOGY AND RESEARCH|technology and technical regulations|biotechnology
    próitéin Cas ion-núicléáis-uireasach Tagairt "Faofa ag an gCoiste Téarmaíochta, www.tearma.ieFaomhadh an téarma seo mar chuid de Thionscadal Lex"
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    dCas Tagairt "Faofa ag an gCoiste Téarmaíochta, www.tearma.ieFaomhadh an téarma seo mar chuid de Thionscadal Lex"
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    dCas | endonuclease-deficient Cas protein | nuclease-dead Cas | dead Cas
    en
    Sainmhíniú "Cas protein with no nuclease [ IATE:1478919/EN ] activity but which retains its other functions" Tagairt "COM-Terminology Coordination, based on: - Regina Mirgayazova, Raniya Khadiullina, Vitaly Chasov, Rimma Mingaleeva, Regina Miftakhova, Albert Rizvanov and Emil Bulatov. 'Therapeutic Editing of the TP53 Gene: Is CRISPR/Cas9 an Option?' (15.1.2021) Genes 2020, 11(6), 704- Yang et al., 2019, 'Dynamic Imaging of RNA in LivingCells by CRISPR-Cas13 Systems' (15.1.2021). Molecular Cell 76, 981–997 December 19, 2019. 2019 Elsevier Inc."
    Nóta The dCas9 is a non-functional nuclease that still retains the ability to bind DNA in an sgRNA-mediated manner, while dCas13s still allow robust real-time imaging and tracking of RNAs in live cells
    dCas | dCas9 | dCas13
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