Gaois

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21 results

  1. SCIENCE|natural and applied sciences|physical sciences|chemistry
    críochphointe Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    Endpunkt | Titrationsendpunkt
    de
    Definition derjenige Punkt bei einer Titration, bei dem sich eine ausgewählte Eigenschaft der Lösung (z. B. die ihr durch einen Indikator verliehene Farbe ...) deutlich ändert Reference "Thieme RÖMPP Online, Eintrag zu ""Endpunkt"", Thieme, 2010, https://roempp.thieme.de/roempp4.0/do/data/RD-05-01085 (20.7.2017)"
    Comment "Der Endpunkt liegt mehr oder weniger direkt am Äquivalenzpunkt (theoretischer Endpunkt). Bei der graphischen Methode der Bestimmung des Endpunktes wird dieser als Schnittpunkt von zwei Geraden oder Kurven erhalten.Quelle: Thieme RÖMPP Online, Eintrag zu ""Endpunkt"", Thieme, 2010, https://roempp.thieme.de/roempp4.0/do/data/RD-05-01085 (20.7.2017).Siehe auch: - Äquivalenzpunkt [ IATE:1581531 ]- Titration [ IATE:1594555 ]"
    endpoint | end point
    en
    Definition the point in the titration once the equivalence point has been reached, indicated by some form of indicator which varies depending on the type of titration being done Reference "UC Davis, Titration Fundamentals, http://chemwiki.ucdavis.edu/Analytical_Chemistry/Quantitative_Analysis/Titration/Titration_Fundamentals [20.11.2015]"
    Comment "If a color indicator is used, the solution will change color when the titration is at its end point.The endpoint of a titration is NOT the same thing as the equivalence point. The equivalence point is a single point defined by the reaction stoichiometry as the point at which the base (or acid) added exactly neutralizes the acid (or base) being titrated. The endpoint is defined by the choice of indicator as the point at which the colour changes. Depending on how quickly the colour changes, the endpoint can occur almost instantaneously or be quite wide. If an appropriate indicator is chosen such that the endpoint of the titration occurs at the equivalence point, then a colour change in the solution being titrated can be used as a signal that the equivalence point has been reached. The volume of titrant needed to reach the equivalence point can then be read, allowing us to calculate concentrations, volumes, Ka's etc.See also:- equivalence point [ IATE:1581531 ]- titration [ IATE:1594555 ]"
    point de virage | point final du titrage | point équivalent | point d'équivalence
    fr
  2. SCIENCE|natural and applied sciences|physical sciences|chemistry
    aimsiú críochphointe dathmhéadrach Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    kolorimetrische Endpunktbestimmung
    de
    colorimetric end-point detection | endpoint
    en
    Definition in volumetric analysis, the visual detection of the end-point using a suitable colorimetric indicator Reference "Based on: John P. Sibilia A Guide to Materials Characterization and Chemical Analysis http://books.google.com/books?id=7EuNAQThP_0C&pg=PA116&lpg=PA116&dq=colorimetric+end-point+detection&source=bl&ots=8SLNpl3XQx&sig=ZDctSBEyoc25pDSVFnDFcR2_VEk&hl=en&ei=z16eSsPPKNLb-Qbq34TaCw&sa=X&oi=book_result&ct=result&resnum=5#v=onepage&q=colorimetric%20end-point%20detection&f=false [2.9.2009]"
    détection colorimétrique au point d'équivalence
    fr
  3. SOCIAL QUESTIONS|health|medical science|toxicology
    críochphointe Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    Context 'Féadfar tástáil i ndáil le críochphointe sonrach a fhágáil ar lár i gcás nach féidir, ar bhonn teicniúil, an staidéar a dhéanamh i ngeall ar airíonna na substainte...' Reference "Rialachán (AE) Uimh. 528/2012 maidir le táirgí bithicídeacha a chur ar fáil ar an margadh agus a úsáid, CELEX:32012R0528/GA"
    critéar Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    Endpunkt
    de
    Definition physisches oder chemisches Ergebnis, das anhand von Tests bewertet werden kann Reference "Europäische Behörde für Lebensmittelsicherheit (EFSA) > Mehr erfahren > Glossar > https://www.efsa.europa.eu/de/glossary-taxonomy-terms (25.7.2017)"
    Comment z.B. der Blutdruck oder Konzentrationen eines möglichen Giftstoffs im Körper
    endpoint
    en
    Definition physical or chemical outcome that can be assessed by a test Reference "European Food Safety Authority (EFSA) > Discover > Resources > Glossary, https://www.efsa.europa.eu/en/glossary-taxonomy-terms [19.9.2017]"
    Comment for example, blood pressure or levels of a potential toxin in the body
    critère | caractéristique | point final
    fr
    Definition paramètre par lequel on évalue, au cours d'un essai clinique, les effets d'une intervention Reference "Le Grand Dictionnaire terminologique, http://gdt.oqlf.gouv.qc.ca [16.8.2017]"
  4. EDUCATION AND COMMUNICATIONS|information technology and data processing
    críochphointe Reference "Cinneadh Cur Chun Feidhme (AE) 2023/1795 ón gCoimisiún an 10 Iúil 2023 de bhun Rialachán (AE) 2016/679 ó Pharlaimint na hEorpa agus ón gComhairle maidir leis an leibhéal leormhaith cosanta sonraí pearsanta faoi Chreat Príobháideachais Sonraí AE-SAM(a bhfuil fógra tugtha ina leith faoi dhoiciméad C(2023)4745) (25.4.2024)"
    ga
    Context Meabhrán Slándála Náisiúnta 8 [...] (lena mbunaítear amlínte agus treoraíocht maidir leis an gcaoi a gcuirfear ceanglais chibearshlándála chun feidhme le haghaidh córais slándála náisiúnta, lena n-áirítear fíordheimhniúchán ilfhachtóra, criptiú, néalteicneolaíochtaí agus seirbhísí braite críochphointe) Reference "Cinneadh Cur Chun Feidhme (AE) 2023/1795 ón gCoimisiún an 10 Iúil 2023 de bhun Rialachán (AE) 2016/679 ó Pharlaimint na hEorpa agus ón gComhairle maidir leis an leibhéal leormhaith cosanta sonraí pearsanta faoi Chreat Príobháideachais Sonraí AE-SAM(a bhfuil fógra tugtha ina leith faoi dhoiciméad C(2023)4745) (25.4.2024)"
    Definition aon ghaireas atá nasctha le líonra agus a fheidhmíonn mar phointe iontrála sa líonra sin Reference "Togra le haghaidh Rialachán maidir le ceanglais chothrománacha chibearshlándála le haghaidh táirgí a bhfuil eilimintí digiteacha acu agus lena leasaítear Rialachán (AE) 2019/1020,CELEX:52022PC0454/GA"
    Endpunkt
    de
    Definition Gerät, das an ein Netz angeschlossen ist und als Zugangspunkt zu diesem Netz dient Reference "Vorschlag für eine Verordnung des Europäischen Parlaments und des Rates über horizontale Cybersicherheitsanforderungen für Produkte mit digitalen Elementen und zur Änderung der Verordnung (EU) 2019/1020"
    endpoint | end-point
    en
    Definition any device that is connected to a network and serves as an entry point to that network Reference "Regulation (EU) 2024/2847 on horizontal cybersecurity requirements for products with digital elements and amending Regulations (EU) No 168/2013 and (EU) 2019/1020 and Directive (EU) 2020/1828 (Cyber Resilience Act)"
    point terminal
    fr
    Definition tout dispositif connecté à un réseau et servant de point d’entrée à ce réseau Reference "Proposition de règlement concernant des exigences horizontales en matière de cybersécurité pour les produits comportant des éléments numériques COM(2022)454"
  5. SOCIAL QUESTIONS|health|medical science
    rinn-chríochphointe Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    apikaler Endpunkt
    de
    Definition Auslösen einer Wirkung auf Populationsebene Reference "Verordnung (EU) Nr. 2017/735 der Kommission zur Änderung — zwecks Anpassung an den technischen Fortschritt — des Anhangs der Verordnung (EG) Nr. 440/2008 zur Festlegung von Prüfmethoden gemäß der Verordnung (EG) Nr. 1907/2006 des Europäischen Parlaments und des Rates zur Registrierung, Bewertung, Zulassung und Beschränkung chemischer Stoffe (REACH) CELEX:32017R0735/DE"
    apical endpoint | endpoints | apical effect
    en
    Definition in toxicology studies, empirically verifiable outcomes of exposure, such as developmental anomalies, breeding behaviors, impaired reproduction, physical changes and alterations in the size and histopathology of organs, and, of course, death Reference "Eddy Ball. Committee Proposes Paradigm Shift in Toxicity Testing. NIEHS. Environmental Factor. September 2007. http://www.niehs.nih.gov/news/newsletter/2007/september/toxicitytesting.cfm [25.2.2010]"
    critère d'évaluation apical | critères d'évaluation apicaux | critère apical d'évaluation | critères apicaux d'évaluation
    fr
    Comment "Le besoin de qualifier les critères d'évaluation en toxicologie par l'emploi de l'adjectif ""apical"" ne se fait sentir que lorsqu'on introduit l'idée d'autres critères que les modifications physiologiques observables et mesurables (critères traditionnels). Voir le contexte EN."
  6. SCIENCE|natural and applied sciences|applied sciences · AGRI-FOODSTUFFS|food technology
    críochphointe measúnúcháin Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    assessment endpoint
    en
    Definition explicit expression of the environmental value that is to be protected, operationally defined by an ecological entity and its attributes Reference "Terminology Services, EPA (United States Environmental Protection Agency) > Terms & Acronyms > Assessment Endpoint, https://iaspub.epa.gov/sor_internet/registry/termreg/searchandretrieve/termsandacronyms/search.do?search=&term=assessment%20endpoint&matchCriteria=Contains&checkedAcronym=true&checkedTerm=true&hasDefinitions=false [26.9.2017]"
    Comment "For example, salmon are valued ecological entities; reproduction and age class structure are some of their important attributes. Together ""salmon reproduction and age class structure"" form an assessment endpoint."
  7. SOCIAL QUESTIONS|health|pharmaceutical industry
    críochphointe Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    críochphointe cliniciúil Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    Endpunkt
    de
    Definition festgelegtes Ziel einer klinischen Studie, anhand dessen festgestellt wird, ob eine angewendete Maßnahme (i.d.R. eine medizinische Behandlung) erfolgreich war Reference "vgl. Wikipedia http://de.wikipedia.org/wiki/Prim%C3%A4rer_Endpunkt (13.10.2009)"
    Comment "Es wird unterschieden zwischen primären Endpunkten (Hauptziel einer Studie - z.B. Überlebensrate oder Rückfallrisiko, i.d.R. messbare Größen) und sekundären Endpunkten (zweitrangiges Ziel einer Studie, oftmals nicht messbare Größen wie Schmerzen, Lebensqualität). [ vgl. Wikipedia http://de.wikipedia.org/wiki/Sekund%C3%A4rer_Endpunkt , 13.10.2009]"
    clinical endpoint | clinical trial endpoint | endpoint | end point | end-point
    en
    Definition clinically relevant outcome, accepted in medical practice (e.g. by regulatory guidance or professional society guidelines) and sufficiently sensitive and specific to detect the anticipated effect of the treatment Reference "COM-Terminology Coordination, based on:European Medicines Agency (EMA). 'ICH guideline E17 on general principles for planning and design of multi-regional clinical trials Step 5' (14.12.2023)"
    Comment "A clinical trial might use a clinical endpoint or a surrogate endpoint. A clinical endpoint is an outcome that represents direct clinical benefit, such as survival, decreased pain, or the absence of disease."
    critère d'évaluation principal | critère d'efficacité | critère de jugement
    fr
    Definition paramètre par lequel on évalue, au cours d'un essai clinique, les effets d'une intervention thérapeutique chez des sujets Reference "Office québecois de la langue française > Grand dictionnaire terminologique > critère d'évaluation (21.9.2023)"
  8. SOCIAL QUESTIONS|health|pharmaceutical industry
    críochphointe comhpháirte Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    component endpoint | singleton endpoint
    en
    Definition "any distinct endpoint that forms a composite endpoint or a multi-component endpoint" Reference "COM-Terminology Coordination, based on: McCoy CE. 'Understanding the Use of Composite Endpoints in Clinical Trials' (2.6.2023). Western Journal of Emergency Medicine 2018 Jul;19(4):631-634. doi: 10.5811/westjem.2018.4.38383. Epub 2018 Jun 4. PMID: 30013696; PMCID: PMC6040910."
  9. SOCIAL QUESTIONS|health|pharmaceutical industry
    críochphointe cumaisc Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    composite endpoint | combined endpoint
    en
    Definition endpoint consisting in more than one endpoints combined into a single variable and representing the occurrence or realisation in a patient of any one of the specified components Reference "COM-Terminology Coordination, based on: FDA. 'Multiple Endpoints in Clinical Trials Guidance for Industry' (2.6.2023)"
  10. SOCIAL QUESTIONS|health|pharmaceutical industry
    críochphointe comhphríomhúil Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    co-primary endpoint
    en
    Definition "any of a set of outcomes that establishes the efficacy, and/or safety features, of a medicinal product in order to support regulatory action where there are two or more different features that are so critically important to the disease under study that a medicinal product will not be considered effective without demonstration of a treatment effect on all of these disease features" Reference "COM-Terminology Coordination, based on: FDA. 'Multiple Endpoints in Clinical Trials Guidance for Industry' (2.6.2023)"
  11. SOCIAL QUESTIONS|health|pharmaceutical industry · PRODUCTION, TECHNOLOGY AND RESEARCH|research and intellectual property|research
    críochphointe éifeachtúlachta Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    Context 'I gcás trialacha cliniciúla a chuirfear i gcrích i ngalar ardghalrachta nó ardmhortlaíochta, áfach, más rud é go bhféadfadh sé gur FDTNA-anna iad críochphointí éifeachtúlachta nó inar mortlaíocht nó toradh “tromchúiseach” eile (a fhéadfar a thuairisciú go hionchasach mar FDTNA) an críochphointe éifeachtúlachta i dtriail chliniciúil, féadfar sláine na trialach cliniciúla a chur i mbaol má bhristear an dalladh go córasach.' Reference "Rialachán (AE) Uimh. 536/2014 maidir le trialacha cliniciúla ar tháirgí íocshláinte lena n-úsáid ag an duine, agus lena n-aisghairtear Treoir 2001/20/CE, CELEX:32014R0536/GA"
    Wirksamkeits-Endpunkt
    de
    efficacy endpoint | efficacy end-point
    en
    Definition "endpoint intended to reflect the effects of a medicinal product" Reference "COM-Terminology Coordination, based on: FDA. 'Multiple Endpoints in Clinical Trials Guidance for Industry' (2.6.2023)"
    Comment "There a can be primary or secondary efficacy endpoints, as secondary endpoints also may provide evidence that a particular mechanism underlies a demonstrated clinical effect (e.g., a drug for osteoporosis with fractures as the primary endpoint, and improved bone density as a secondary endpoint)."
  12. SOCIAL QUESTIONS|health|medical science
    críochphointe géiniteach Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    genetischer Endpunkt
    de
    genetic endpoint | endpoints
    en
    Definition genetic effect defined so that tests can be done to evaluate the distribution of genetic traits in different populations in order to gain insight into factors affecting such distribution Reference "COM-Terminology Coordination, based on:Muin J. Khoury, Terri H. Beaty, Bernice H. Cohen. Fundamentals of Genetic Epidemiology. Oxford. Oxford University Press 1993, https://books.google.be/books?id=-pz8YE8Of84C&pg=PA122&lpg=PA122&dq=genetic+endpoint+is+defined+as&source=bl&ots=cuZg_ZtM3V&sig=LEQ10J3JYpdho4rpk_vxON4IBy4&hl=en&sa=X&ei=wYrYVPDgM5OR7Aa1noCYAQ&ved=0CFUQ6AEwBw#v=onepage&q=genetic%20endpoint%20is%20defined%20as&f=false [13.2.2014]"
    effet génétique recherché
    fr
  13. SOCIAL QUESTIONS|health|pharmaceutical industry
    críochphointe ilchomhpháirte Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    multi-component endpoint
    en
    Definition within-patient combination of two or more components where evaluation is dependent upon observation of all of the specified components in that patient Reference "COM-Terminology Coordination, based on: FDA. 'Multiple Endpoints in Clinical Trials Guidance for Industry' (2.6.2023)"
    Comment A single overall rating or status is determined according to specified rules.
  14. SOCIAL QUESTIONS|health|pharmaceutical industry
    príomh-chríochphointe Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    Context 'Beidh an príomh-chríochphointe iomchuí don fheiste agus beidh sé ábhartha go cliniciúil.' Reference "Rialachán (AE) 2017/745 maidir le feistí leighis, lena leasaítear Treoir 2001/83/CE, Rialachán (CE) Uimh. 178/2002 agus Rialachán (CE) Uimh. 1223/2009 agus lena n-aisghairtear Treoir 90/385/CEE ón gComhairle agus Treoir 93/42/CEE ón gComhairle, CELEX:32017R0745/GA"
    primary endpoint | primary end point | primary end-point | primary clinical endpoint
    en
    Definition "outcome that establishes the efficacy, and/or safety features, of a medicinal product and for which a trial is powered" Reference "COM-Terminology Coordination, based on: - FDA. 'Multiple Endpoints in Clinical Trials Guidance for Industry' (2.6.2023)- Wikipedia > 'Clinical endpoint' (2.6.2023)"
  15. SOCIAL QUESTIONS|health|pharmaceutical industry
    críochphointe sábháilteachta Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    safety endpoint
    en
    Definition "endpoint intended to reflect the safety of a medicinal product" Reference "COM-Terminology Coordination, based on: Meredith Brown-Tuttle. 'The Regulatory Strategist Toolbox: Clinical Endpoint Analysis Tools' (2.6.2023). Regulatory Affairs Professionals Society"
  16. SOCIAL QUESTIONS|health|pharmaceutical industry
    críochphointe tánaisteach Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    secondary endpoint
    en
    Definition "any parameter (endpoint) that can be selected to demonstrate additional effects after success on the primary endpoint" Reference "COM-Terminology Coordination, based on: FDA. 'Multiple Endpoints in Clinical Trials Guidance for Industry' (2.6.2023)"
    Comment Secondary endpoints may also provide evidence that a particular mechanism underlies a demonstrated clinical effect (e.g. a drug for osteoporosis with fractures as the primary endpoint, and improved bone density as a secondary endpoint).
  17. SOCIAL QUESTIONS|health|pharmaceutical industry
    críochphointe ionaid Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    surrogate endpoint
    en
    Definition "in clinical trials, measure of the effect of a specific treatment that may correlate with a real clinical endpoint but does not necessarily have a guaranteed relationship" Reference "COM-Terminology Coordination, based on: COMMISSION STAFF WORKING DOCUMENT IMPACT ASSESSMENT Strengthening of the EU Cooperation on Health Technology Assessment (HTA) Accompanying the document Proposal for a Regulation of the European Parliament and of the Council on health technology assessment and amending Directive 2011/24/EU"
    Comment For example, the serum cholesterol concentration may be considered a surrogate endpoint when assessing pharmaceuticals aiming to prevent complications of cardiovascular disease. However, only about 10% of those with serum cholesterol concentration above the reference range are going to have a stroke or heart attack. Therefore more relevant clinical endpoints could be the number of nonfatal myocardial infarction or stroke cases.
    marqueur de substitution | critère de substitution | critère d'évaluation de substitution
    fr
    Definition marqueur aisément mesurable qui permet, en l’absence de données cliniques, d’évaluer l’effet d’un traitement Reference "Délégation générale à la langue française et aux langues de France (DGLFLF), FranceTerme, fiche ""marqueur de substitution"" (30.7.2020)"
  18. SOCIAL QUESTIONS|health|pharmaceutical industry
    críochphointe treasach Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    tertiary endpoint
    en
    Definition endpoint that generates hypotheses for future studies Reference "COM-Terminology Coordination, based on: Angela B. Smith. 'FDA Workshop: Clinical Trial Design for NMIBC Patient-Reported Outcome Measures' (2.6.2023) November 18-19, 2021"
  19. SCIENCE|natural and applied sciences
    críochphointe scrúdaithe Reference Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    test endpoint
    en
    Definition the general factor that will be changed by the test chemical relative to the control as aim of the test Reference "Commission Regulation (EC) No 761/2009 amending, for the purpose of its adaptation to technical progress, Regulation (EC) No 440/2008 laying down test methods pursuant to Regulation (EC) No 1907/2006 of the European Parliament and of the Council on the Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH) CELEX:32009R0761/EN"
    effet étudié
    fr
    Definition décrit le facteur général qui sera modifié, par rapport au témoin, par la substance d’essai. Dans cette méthode, l’effet étudié est l’inhibition de la croissance qui peut être exprimée par différentes variables étudiées déduites d’une ou de plusieurs variables mesurées Reference "Règlement (CE) no761/2009 de la Commission du 23 juillet 2009 modifiant, aux fins de son adaptation au progrès technique, le règlement (CE) no 440/2008 établissant des méthodes d'essai conformément au règlement (CE) no 1907/2006 du Parlement européen et du Conseil concernant l'enregistrement, l'évaluation et l'autorisation des substances chimiques, ainsi que les restrictions applicables à ces substances (REACH) , JO L 220 du 24 août 2009 , http://eur-lex.europa.eu/LexUriServ/LexUriServ.do?uri=OJ:L:2009:220:0001:0094:FR:PDF"