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SOCIAL QUESTIONS|health|medical science
measúnacht fótatocsaineachta um iontógáil dhearg neodrach 3T3 Tagairt Faomhadh an téarma seo mar chuid de Thionscadal Lex
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tástáil fótatocsaineachta 3T3 NRU Tagairt Faomhadh an téarma seo mar chuid de Thionscadal Lex
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3T3 NRU PT | in vitro | 3T3 Neutral Red Uptake Phototoxicity Assay | 3T3 NRU phototoxicity test
en
Sainmhíniú test used to identify the phototoxic effect of a test substance induced by the combination of test substance and light and is based on the comparison of the cytotoxic effect of a test substance when tested after the exposure and in the absence of exposure to a non-cytotoxic dose of UVA/vis light. Cytotoxicity is expressed as a concentration-dependent reduction of the uptake of the vital dye - Neutral Red. Tagairt MB Research Labs. General Background http://3t3nru.mbresearchlabs.com/background.htm [12.4.2011]
Nóta The 3T3 NRU PT test was developed and validated in a joint EU/COLIPA project from 1992-1997.In 1996, the 3T3 NRU PT was recommended by OECD as an in vitro approach for the assessment of chemicals phototoxicity potential.In April 2004, the 3T3 NRU PT protocol was finalized and adopted as the OECD 432 protocol, in vitro 3T3 NRU phototoxicity test [ IATE:3529845 ].